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Pom121 Gene Detail
Summary
  • Symbol
    Pom121
  • Name
    nuclear pore membrane protein 121
  • Synonyms
    2610027A18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137624
    NCBI Gene: 107939
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:135404995-135423400 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 75.16 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    465 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137624
 protein coding gene Chr5:135404994-135433587 (-)
129S1/SvImJ ENSMUSG00200043963
 protein coding gene Chr5:129189279-129207686 (-)
A/J ENSMUSG00195048818
 protein coding gene Chr5:128695837-128714246 (-)
AKR/J ENSMUSG00220045777
 protein coding gene Chr5:128183226-128201637 (-)
BALB/cJ ENSMUSG00180041581
 protein coding gene Chr5:128800552-128818960 (-)
C3H/HeJ ENSMUSG00175037193
 protein coding gene Chr5:130726646-130745051 (-)
C57BL/6NJ ENSMUSG00215047673
 protein coding gene Chr5:128845570-128863977 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027836
 protein coding gene Chr5:128209208-128227789 (-)
CAST/EiJ ENSTCUG00005010454
 protein coding gene Chr5:128084159-128102842 (-)
CBA/J ENSMUSG00210007485
 protein coding gene Chr5:129544277-129562682 (-)
DBA/2J ENSMUSG00185051253
 protein coding gene Chr5:132559549-132577955 (-)
FVB/NJ ENSMUSG00205039560
 protein coding gene Chr5:128447482-128465894 (-)
JF1/MsJ ENSUMUG00000036007
 protein coding gene Chr5:135453168-135471643 (-)
LP/J ENSMUSG00230048433
 protein coding gene Chr5:136675067-136693473 (-)
NOD/ShiLtJ ENSMUSG00190034956
 protein coding gene Chr5:128501019-128519423 (-)
NZO/HlLtJ ENSMUSG00225022695
 protein coding gene Chr5:144354762-144373168 (-)
PWK/PhJ ENSLUMG00010014276
 protein coding gene Chr5:127302894-127321324 (-)
SPRET/EiJ ENSMSPG00010030549
 protein coding gene Chr5:130708948-130727461 (-)
WSB/EiJ ENSIUOG00005029850
 protein coding gene Chr5:131147489-131165803 (-)



Homology
more
  • Human Ortholog
    POM121, POM121 transmembrane nucleoporin
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POM121, POM121 transmembrane nucleoporin
  • Synonyms
    P145, POM121A
  • Links
    NCBI Gene ID: 9883
    UniProt: Q96HA1

  • Chr Location
    7q11.23; chr7:72879349-72951459 (+)  GRCh38
  • Human Ortholog
    POM121B, POM121 transmembrane nucleoporin B (pseudogene)
  • Links
    NCBI Gene ID: 100288540
    UniProt: A6NF01

  • Chr Location
    chr7:73293495-73303235 (+)  GRCh38
  • Human Ortholog
    POM121C, POM121 transmembrane nucleoporin C
  • Synonyms
    POM121-2
  • Links
    NCBI Gene ID: 100101267
    UniProt: A8CG34

  • Chr Location
    7q11.23; chr7:75416784-75486358 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    651
  • Tissues
    41
  • cDNA Data
    9
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053293 Ensembl Gene Model | MGI Sequence Detail 18406 C57BL/6J ±  kb
transcript ENSMUST00000111171 Ensembl | MGI Sequence Detail 5580 Not Applicable  
polypeptide ENSMUSP00000106801 Ensembl | MGI Sequence Detail 1200 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013012 nuclear envelope pore membrane protein POM 121C
    (term hierarchy)
  • InterPro Domains
    IPR026054 Nuclear pore complex protein
  • GlyGen
    Q8K3Z9 22 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (15 sites)
Molecular
Reagents
less
  • All nucleic 15
    Genomic 4
    cDNA 9
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1916472, MGI:2141316
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory