About   Help   FAQ
Arid4b
Gene Detail
Symbol

Name
ID
Arid4b
AT rich interactive domain 4B (RBP1-like)
MGI:2137512
Synonyms
6330417L24Rik, 6720480E17Rik, BRCAA1, RBBP1L1, Rbp1l1, SAP180
Feature Type
protein coding gene
Genetic Map
Chromosome 13
5.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr13:14063232-14199367 bp, + strand
From VEGA annotation of GRCm38

  136136 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12847  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ARID4B
Protein SuperFamily: AT-rich interactive domain-containing protein 4 (retinoblastoma binding protein 1)
Gene Tree: Arid4b

Human
homologs
ARID4B, AT rich interactive domain 4B (RBP1-like)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 51742
neXtProt AC: NX_Q4LE39

Human Synonyms: BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180

Human Chr (Location): 1q42.3; chr1:235166895-235328298 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(36) : Gene trapped(33) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null allele die pre-implantation.
 
Mutations Annotated to Human Diseases (1)   
Interactions
Arid4b interacts with 405 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process establishment of Sertoli cell barrier, histone H3-K9 trimethylation, ...
Component nucleus
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(103)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase arid4b ; ZFIN arid4b    NEW 
Molecular
reagents
All nucleic(108) Genomic(4) cDNA(103) Primer pair(1)
Microarray probesets(12)
Other database
links
VEGA Gene Model OTTMUSG00000018144 (Evidence)
Ensembl Gene Model ENSMUSG00000039219 (Evidence)
Entrez Gene 94246 (Evidence)
UniGene 439784
DFCI TC1598142, TC1599976, TC1604199, TC1583386, TC1602126, TC1607157
DoTS DT.55249967, DT.529776, DT.91551899, DT.101167332, DT.101368468, DT.101368467, DT.94374405
Consensus CDS Project CCDS36599.1, CCDS36600.1
International Mouse Phenotyping Consortium Status Arid4b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018144 VEGA Gene Model | MGI Sequence Detail 136136 C57BL/6J ±  kb
transcript OTTMUST00000041785 VEGA | MGI Sequence Detail 5864 Not Applicable 
polypeptide OTTMUSP00000018788 VEGA | MGI Sequence Detail 1314 Not Applicable 

For the selected sequences
All sequences(92) RefSeq(11) UniProt(8)
Polymorphisms
PCR(1) : SNPs within 2kb(580 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001606 ARID/BRIGHT DNA-binding domain
InterPro IPR016197 Chromo domain-like
InterPro IPR000953 Chromo domain/shadow
InterPro IPR012603 RBB1NT
InterPro IPR025995 RNA binding activity-knot of a chromodomain
InterPro IPR002999 Tudor domain
Protein Ontology PR:000004268 AT-rich interactive domain-containing protein 4B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:210434 Wu RC, et al., ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4616-21
All references(43)
Other
accession IDs
MGI:1917988, MGI:1924943

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2015
MGI 5.22
The Jackson Laboratory