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Arid4b Gene Detail
Summary
  • Symbol
    Arid4b
  • Name
    AT rich interactive domain 4B (RBP1-like)
  • Synonyms
    6330417L24Rik, 6720480E17Rik, BRCAA1, RBBP1L1, Rbp1l1, SAP180
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137512
    NCBI Gene: 94246
  • Gene Overview
    MyGene.info: ARID4B
Location & Maps
more
  • Sequence Map
    Chr13:14063232-14199367 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      136136 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 5.29 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ARID4B, AT-rich interaction domain 4B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARID4B, AT-rich interaction domain 4B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180
  • Links
    NCBI Gene ID: 51742
    neXtProt AC: NX_Q4LE39

  • Chr Location
    1q42.3; chr1:235166895-235328298 (-)  GRCh38.p2

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    32 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele die pre-implantation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018144 VEGA Gene Model | MGI Sequence Detail 136136 C57BL/6J ±  kb
transcript OTTMUST00000041785 VEGA | MGI Sequence Detail 5864 Not Applicable  
polypeptide OTTMUSP00000018788 VEGA | MGI Sequence Detail 1314 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    575 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 108
    Genomic 4
    cDNA 103
    Primer pair 1

    Microarray probesets 12
Other
Accession IDs
less
MGI:1917988, MGI:1924943
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:233398 Wu RC, et al., Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. Mol Endocrinol. 2015 Sep;29(9):1334-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory