Arid4b
Gene Detail

Symbol Name ID

Arid4b AT rich interactive domain 4B (RBP1-like) MGI:2137512

Synonyms

6330417L24Rik, 6720480E17Rik, BRCAA1, RBBP1L1, Rbp1l1, SAP180

Feature Type

protein coding gene

Genetic Map

Chromosome 13

5.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr13:14063232-14199367 bp, + strand From VEGA annotation of GRCm38   136136 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:12847  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: AT-rich interactive domain-containing protein 4 (retinoblastoma binding protein 1)
Gene Tree: Arid4b

Human homologs

Human Homolog		ARID4B, AT rich interactive domain 4B (RBP1-like)
NCBI Gene ID		51742
neXtProt AC		NX_Q4LE39
Human Synonyms		BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180
Human Chr (Location)		1q42.1-q43; chr1:235330210-235491532 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(36) : Targeted(3) Gene trapped(33)
 

Mice homozygous for a null allele die pre-implantation.

 
Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	histone H3-K9 trimethylation, histone H4-K20 trimethylation, ...
Component	intracellular, nucleus
Function	DNA binding

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(104)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(109) Genomic(4) cDNA(104) Primer pair(1)
Microarray probesets(12)

Other database links

VEGA Gene Model	OTTMUSG00000018144 (Evidence)
Ensembl Gene Model	ENSMUSG00000039219 (Evidence)
Entrez Gene	94246 (Evidence)
UniGene	439784
DFCI	TC1583386, TC1598142, TC1599976, TC1602126, TC1604199, TC1607157
DoTS	DT.101167332, DT.101368467, DT.101368468, DT.529776, DT.55249967, DT.91551899, DT.94374405
Consensus CDS Project	CCDS36599.1, CCDS36600.1
International Mouse Knockout Project Status	Arid4b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000018144	VEGA Gene Model | MGI Sequence Detail	136136	C57BL/6J
transcript	OTTMUST00000041785	VEGA | MGI Sequence Detail	5864	Not Applicable
polypeptide	OTTMUSP00000018788	VEGA | MGI Sequence Detail	1314	Not Applicable

All sequences(82) RefSeq(4) UniProt(6)

Polymorphisms

PCR(1) : SNPs(537 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001606	ARID/BRIGHT DNA-binding domain
InterPro	IPR016197	Chromo domain-like
InterPro	IPR000953	Chromo domain/shadow
InterPro	IPR012603	RBB1NT
InterPro	IPR025995	RNA binding activity-knot of a chromodomain
InterPro	IPR002999	Tudor domain
Protein Ontology	PR:000004268	AT-rich interactive domain-containing protein 4B

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183391 Mann KM, et al., Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5934-41
All references(41)

Other accession IDs

MGI:1917988, MGI:1924943