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Arid4b Gene Detail
Summary
  • Symbol
    Arid4b
  • Name
    AT rich interactive domain 4B (RBP1-like)
  • Synonyms
    6330417L24Rik, 6720480E17Rik, BRCAA1, RBBP1L1, Rbp1l1, SAP180
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137512
    NCBI Gene: 94246
  • Gene Overview
    MyGene.info: ARID4B
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:14063609-14199603 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 5.29 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    577 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137512
protein coding gene Chr13:14063232-14199603 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020242
protein coding gene Chr13:11032372-11175592 (+)
A/J MGP_AJ_G0020200
protein coding gene Chr13:10956136-11095891 (+)
AKR/J MGP_AKRJ_G0020174
protein coding gene Chr13:11074843-11222710 (+)
BALB/cJ MGP_BALBcJ_G0020186
protein coding gene Chr13:10937660-11079460 (+)
C3H/HeJ MGP_C3HHeJ_G0019990
protein coding gene Chr13:11235574-11384825 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020630
protein coding gene Chr13:11605851-11764357 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018236
protein coding gene Chr13:9687381-9831315 (+)
CAST/EiJ MGP_CASTEiJ_G0019523
protein coding gene Chr13:10893928-11044644 (+)
CBA/J MGP_CBAJ_G0019954
protein coding gene Chr13:11964471-12127005 (+)
DBA/2J MGP_DBA2J_G0020073
protein coding gene Chr13:10606308-10739330 (+)
FVB/NJ MGP_FVBNJ_G0020054
protein coding gene Chr13:10365920-10508112 (+)
LP/J MGP_LPJ_G0020143
protein coding gene Chr13:11217743-11386736 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020091
protein coding gene Chr13:12065078-12236871 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020657
protein coding gene Chr13:10878677-11027118 (+)
PWK/PhJ MGP_PWKPhJ_G0019287
protein coding gene Chr13:10681489-10837950 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019094
protein coding gene Chr13:10045692-10218394 (+)
WSB/EiJ MGP_WSBEiJ_G0019585
protein coding gene Chr13:10900940-11050424 (+)



Homology
more
  • Human Ortholog
    ARID4B, AT-rich interaction domain 4B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARID4B, AT-rich interaction domain 4B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180
  • Links
    NCBI Gene ID: 51742
    neXtProt AC: NX_Q4LE39
    UniProt: Q4LE39

  • Chr Location
    1q42.3; chr1:235166895-235328240 (-)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 2 alleles in 2 genetic backgrounds
    32 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele die pre-implantation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94246 NCBI Gene Model | MGI Sequence Detail 135995 C57BL/6J ±  kb
transcript NM_194262 RefSeq | MGI Sequence Detail 6113 C57BL/6  
polypeptide A2CG63 UniProt | EBI | MGI Sequence Detail 1314 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 109
    Genomic 4
    cDNA 104
    Primer pair 1

    Microarray probesets 12
Other
Accession IDs
less
MGI:1917988, MGI:1924943
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:250205 Wu RC, et al., Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network. Stem Cells. 2017 Jun;35(6):1554-1565

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory