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Kifc5b Gene Detail
Summary
  • Symbol
    Kifc5b
  • Name
    kinesin family member C5B
  • Synonyms
    kinesin family c-terminal 5B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137414
    NCBI Gene: 16580
  • Gene Overview
    MyGene.info: KIFC1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26917091-26932579 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.60 cM
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137414
protein coding gene Chr17:26917091-26932579 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023408
protein coding gene Chr17:26128719-26157016 (+)
A/J MGP_AJ_G0023500
protein coding gene Chr17:32649667-32673051 (-)
AKR/J MGP_AKRJ_G0023466
protein coding gene Chr17:33030994-33048964 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023814
protein coding gene Chr17:27231536-27262906 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021287
protein coding gene Chr17:22757821-22773889 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0023238
protein coding gene Chr17:24904189-24924962 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0023314
protein coding gene Chr17:26377137-26406950 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023361
protein coding gene Chr17:35551274-35570476 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023854
protein coding gene Chr17:25834121-25865832 (+)
PWK/PhJ MGP_PWKPhJ_G0022383
protein coding gene Chr17:23699633-23723556 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022201
protein coding gene Chr17:23868931-23882365 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KIFC1, kinesin family member C1
  • Vertebrate Orthologs
    12
  • Human Ortholog
    KIFC1, kinesin family member C1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSET, KNSL2
  • Links
    NCBI Gene ID: 3833
    neXtProt AC: NX_Q9BW19
    UniProt: Q9BW19

  • Chr Location
    6p21.32; chr6:33391524-33410226 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 83229
    1 human;2 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;2 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KIFC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16580 NCBI Gene Model | MGI Sequence Detail 15489 C57BL/6J ±  kb
transcript NM_053173 RefSeq | MGI Sequence Detail 2627 C57BL/6  
polypeptide NP_444403 RefSeq | MGI Sequence Detail 672 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 21
    cDNA 19
    Primer pair 1
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:39117 Saito N, et al., KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron. 1997 Mar;18(3):425-38
  • Latest
    J:226736 Li X, et al., Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory