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Slc28a3 Gene Detail
Summary
  • Symbol
    Slc28a3
  • Name
    solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
  • Synonyms
    Cnt3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137361
    NCBI Gene: 114304
Location & Maps
more
  • Sequence Map
    Chr13:58545399-58610877 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      65479 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 31.07 cM, cytoband B2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC28A3, solute carrier family 28 member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC28A3, solute carrier family 28 member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CNT3
  • Links
    NCBI Gene ID: 64078
    neXtProt AC: NX_Q9HAS3

  • Chr Location
    9q22.2; chr9:84275850-84368632 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    2
  • Genomic Mutations
    1 involving Slc28a3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032647 VEGA Gene Model | MGI Sequence Detail 65479 C57BL/6J ±  kb
transcript OTTMUST00000081221 VEGA | MGI Sequence Detail 4567 Not Applicable  
polypeptide OTTMUSP00000043408 VEGA | MGI Sequence Detail 703 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    520 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015053 solute carrier family 28 member 3
  • InterPro Domains
    IPR008276 Concentrative nucleoside transporter
    IPR030211 Concentrative nucleoside transporter CNT3
    IPR011657 Concentrative nucleoside transporter C-terminal domain
    IPR018270 Concentrative nucleoside transporter, metazoan/bacterial
    IPR002668 Concentrative nucleoside transporter N-terminal domain
    IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain
Molecular
Reagents
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  • All nucleic 81
    cDNA 80
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:70326 Ritzel MW, et al., Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). J Biol Chem. 2001 Jan 26;276(4):2914-27
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory