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Trim33
Gene Detail
Symbol

Name
ID
Trim33
tripartite motif-containing 33
MGI:2137357
Synonyms
8030451N04Rik, Ecto, ectodermin, mKIAA1113, Tif1g
Feature Type
protein coding gene
Genetic Map
Chromosome 3
45.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:103279293-103358768 bp, + strand
From Ensembl annotation of GRCm38

  79476 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9296  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: TRIM33
Gene Tree: Trim33

Human
homologs
TRIM33, tripartite motif containing 33
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51592
neXtProt AC: NX_Q9UPN9

Human Synonyms: ECTO, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA

Human Chr (Location): 1p13.1; chr1:114392777-114511160 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TRIM33

Mutations,
alleles, and
phenotypes
All mutations/alleles(32) : Gene trapped(25) Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit embryonic lethality prior to E9.5 with abnormal embryonic development.
 
Interactions
Trim33 interacts with 458 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Expression
Literature Summary: (7 records)
Data Summary: Results (76)    Tissues (48)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 76
cDNA source data(127)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase trim33 ; ZFIN trim33    NEW 
Molecular
reagents
All nucleic(128) cDNA(127) Primer pair(1)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000033014 (Evidence)
Entrez Gene 94093 (Evidence)
UniGene 195036
DFCI TC1576747, TC1597560, TC1614933, TC1697831, TC1719088
DoTS DT.101740211, DT.40146651, DT.491043, DT.87028428, DT.91446989
NIA Mouse Gene Index U003664
EC 6.3.2.-
Consensus CDS Project CCDS38573.1, CCDS38574.1
International Mouse Phenotyping Consortium Status Trim33
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033014 Ensembl Gene Model | MGI Sequence Detail 79476 C57BL/6J ±  kb
transcript ENSMUST00000029444 Ensembl | MGI Sequence Detail 8868 Not Applicable 
polypeptide ENSMUSP00000029444 Ensembl | MGI Sequence Detail 1140 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(5) UniProt(6)
Polymorphisms
SNPs within 2kb(266 from dbSNP Build 137)    SNPs within 2kb including multiple locations(268)
Protein-related
information
ResourceIDDescription
InterPro IPR003649 B-box, C-terminal
InterPro IPR001487 Bromodomain
InterPro IPR000315 Zinc finger, B-box
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000016655 E3 ubiquitin-protein ligase TRIM33
References
(Earliest) J:69273 Reymond A, et al., The tripartite motif family identifies cell compartments. EMBO J. 2001 May 1;20(9):2140-51
(Latest) J:212263 Quere R, et al., Tif1gamma regulates the TGF-beta1 receptor and promotes physiological aging of hematopoietic stem cells. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10592-7
All references(52)
Other
accession IDs
MGI:2139690, MGI:2444632

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory