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Trim16 Gene Detail
Summary
  • Symbol
    Trim16
  • Name
    tripartite motif-containing 16
  • Synonyms
    9130006M08Rik, EBBP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137356
    NCBI Gene: 94092
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:62711034-62733774 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 38.75 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    225 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137356
protein coding gene Chr11:62711034-62741634 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018463
protein coding gene Chr11:62902795-62940773 (+)
A/J MGP_AJ_G0018432
protein coding gene Chr11:60565436-60596997 (+)
AKR/J MGP_AKRJ_G0018401
protein coding gene Chr11:62433677-62464415 (+)
BALB/cJ MGP_BALBcJ_G0018403
protein coding gene Chr11:60844209-60875555 (+)
C3H/HeJ MGP_C3HHeJ_G0018216
protein coding gene Chr11:62407269-62439772 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018855
protein coding gene Chr11:64875298-64906846 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016499
protein coding gene Chr11:57646012-57677257 (+)
CAST/EiJ MGP_CASTEiJ_G0017772
protein coding gene Chr11:62560434-62597661 (+)
CBA/J MGP_CBAJ_G0018190
protein coding gene Chr11:67666543-67704220 (+)
DBA/2J MGP_DBA2J_G0018299
protein coding gene Chr11:60117244-60149241 (+)
FVB/NJ MGP_FVBNJ_G0018289
protein coding gene Chr11:59784952-59817063 (+)
LP/J MGP_LPJ_G0018371
protein coding gene Chr11:63435548-63469409 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018313
protein coding gene Chr11:68648656-68688320 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018896
protein coding gene Chr11:62590076-62623140 (+)
PWK/PhJ MGP_PWKPhJ_G0017546
protein coding gene Chr11:60735519-60768877 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017336
protein coding gene Chr11:62436234-62474454 (+)
WSB/EiJ MGP_WSBEiJ_G0017825
protein coding gene Chr11:62208249-62240662 (+)



Homology
more
  • Human Ortholog
    TRIM16, tripartite motif containing 16
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM16, tripartite motif containing 16
  • Synonyms
    EBBP
  • Links
    NCBI Gene ID: 10626
    neXtProt AC: NX_O95361
    UniProt: O95361

  • Chr Location
    17p12; chr17:15627966-15682879 (-)  GRCh38.p7

  • Human Ortholog
    TRIM16L, tripartite motif containing 16 like
  • Synonyms
    TRIM70
  • Links
    NCBI Gene ID: 147166
    neXtProt AC: NX_Q309B1
    UniProt: Q309B1

  • Chr Location
    17p11.2; chr17:18697998-18736119 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 94092 NCBI Gene Model | MGI Sequence Detail 22741 C57BL/6J ±  kb
    transcript NM_053169 RefSeq | MGI Sequence Detail 3896 C57BL/6  
    polypeptide Q99PP9 UniProt | EBI | MGI Sequence Detail 556 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      Genomic 1
      cDNA 28

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1918832, MGI:2144201
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:307479 Wang L, et al., Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1. Cell Metab. 2021 Jul 6;33(7):1372-1388.e7

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    06/28/2022
    MGI 6.20
    The Jackson Laboratory