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Trim9 Gene Detail
Summary
  • Symbol
    Trim9
  • Name
    tripartite motif-containing 9
  • Synonyms
    C030048G07Rik, mKIAA0282
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137354
    NCBI Gene: 94090
  • Gene Overview
    MyGene.info: TRIM9
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr12:70244533-70347614 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      103082 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 29.07 cM, cytoband C3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TRIM9, tripartite motif containing 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TRIM9, tripartite motif containing 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RNF91, SPRING
  • Links
    NCBI Gene ID: 114088
    neXtProt AC: NX_Q9C026
    UniProt: Q9C026

  • Chr Location
    14q22.1; chr14:50975261-51105173 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9045
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TRIM9
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display increased axonal branching and increased corpus callosum thickness.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021071 Ensembl Gene Model | MGI Sequence Detail 103082 C57BL/6J ±  kb
    transcript ENSMUST00000222316 Ensembl | MGI Sequence Detail 3049 Not Applicable  
    polypeptide ENSMUSP00000152147 Ensembl | MGI Sequence Detail 817 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1043 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 69
      cDNA 66
      Primer pair 2
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1924734, MGI:2144887
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 12
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:251090 Plooster M, et al., TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching. Mol Biol Cell. 2017 Sep 1;28(18):2374-2385

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/08/2018
    MGI 6.12
    The Jackson Laboratory