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Mrpl1 Gene Detail
Summary
  • Symbol
    Mrpl1
  • Name
    mitochondrial ribosomal protein L1
  • Synonyms
    2410002L03Rik, 5830418D04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137202
    NCBI Gene: 94061
  • Gene Overview
    MyGene.info: MRPL1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:96209498-96266727 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 47.29 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    274 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137202
protein coding gene Chr5:96209493-96266727 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029764
protein coding gene Chr5:97433047-97491152 (+)
A/J MGP_AJ_G0029730
protein coding gene Chr5:93870722-93927884 (+)
AKR/J MGP_AKRJ_G0029676
protein coding gene Chr5:96999367-97056818 (+)
BALB/cJ MGP_BALBcJ_G0029740
protein coding gene Chr5:94867434-94926714 (+)
C3H/HeJ MGP_C3HHeJ_G0029463
protein coding gene Chr5:97323202-97380738 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030195
protein coding gene Chr5:101586948-101645736 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027430
protein coding gene Chr5:89268117-89324139 (+)
CAST/EiJ MGP_CASTEiJ_G0028873
protein coding gene Chr5:95910487-95968836 (+)
CBA/J MGP_CBAJ_G0029433
protein coding gene Chr5:105105065-105166422 (+)
DBA/2J MGP_DBA2J_G0029577
protein coding gene Chr5:94068609-94125869 (+)
FVB/NJ MGP_FVBNJ_G0029536
protein coding gene Chr5:92899072-92956289 (+)
LP/J MGP_LPJ_G0029665
protein coding gene Chr5:98097558-98155229 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029565
protein coding gene Chr5:110197110-110253948 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030228
protein coding gene Chr5:96429631-96486909 (+)
PWK/PhJ MGP_PWKPhJ_G0028592
protein coding gene Chr5:92474367-92531928 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028427
protein coding gene Chr5:94080879-94139098 (+)
WSB/EiJ MGP_WSBEiJ_G0028952
protein coding gene Chr5:96745676-96803622 (+)



Homology
more
  • Human Ortholog
    MRPL1, mitochondrial ribosomal protein L1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MRPL1, mitochondrial ribosomal protein L1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BM022, L1MT, MRP-L1
  • Links
    NCBI Gene ID: 65008
    neXtProt AC: NX_Q9BYD6
    UniProt: Q9BYD6

  • Chr Location
    4q21.1; chr4:77861955-77952790 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41355
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MRPL1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94061 NCBI Gene Model | MGI Sequence Detail 57230 C57BL/6J ±  kb
transcript NM_053158 RefSeq | MGI Sequence Detail 3449 C57BL/6  
polypeptide Q99N96 UniProt | EBI | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010571 39S ribosomal protein L1, mitochondrial
  • InterPro Domains
    IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich
    IPR023674 Ribosomal protein L1-like
    IPR005879 Ribosomal protein L1, mitochondrial
    IPR028364 Ribosomal protein L1/ribosomal biogenesis protein
Molecular
Reagents
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  • All nucleic 49
    cDNA 49

    Microarray probesets 6
Other
Accession IDs
less
MGI:1914850, MGI:1916955, MGI:2140906
References
more
  • Summaries
    All 40
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory