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N4bp1
Gene Detail
Symbol

Name
ID
N4bp1
NEDD4 binding protein 1
MGI:2136825
Synonyms
MGC:7607
Feature Type
protein coding gene
Genetic Map
Chromosome 8
42.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:86841139-86885258 bp, - strand
From Ensembl annotation of GRCm38

  44120 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23703  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: N4bp1

Human
homologs
Human Homolog N4BP1, Nedd4 binding protein 1
NCBI Gene ID 9683
neXtProt AC  NX_O75113
Human Chr (Location)  16q12.1; chr16:48538726-48610214 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(25) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
N4bp1 interacts with 386 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cellular response to UV, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, ...
Component nucleolus, nucleus, ...
Function protein binding, RNA binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000031652 (Evidence)
Entrez Gene80750 (Evidence)
DFCITC1674918, TC1649318, TC1597762, TC1602381, TC1589686, TC1582674
DoTSDT.94264078, DT.101369711, DT.101155603, DT.91592335, DT.110894928
NIA Mouse Gene IndexU030069
Consensus CDS ProjectCCDS52625.1
International Mouse Knockout Project StatusN4bp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031652 Ensembl Gene Model | MGI Sequence Detail 44120 C57BL/6J ±  kb
transcript ENSMUST00000034074 Ensembl | MGI Sequence Detail 6469 Not Applicable 
polypeptide ENSMUSP00000034074 Ensembl | MGI Sequence Detail 893 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(6) UniProt(7)
Polymorphisms
SNPs within 2kb(230 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004088 K Homology domain, type 1
InterPro IPR021869 Ribonuclease Zc3h12a-like
Protein Ontology PR:000010937 NEDD4-binding protein 1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173792 Bracken CP, et al., Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Res. 2011 Mar 22;
All references(37)
Other
accession IDs
MGI:2142573, MGI:2142863

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory