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N4bp1
Gene Detail
Symbol

Name
ID
N4bp1
NEDD4 binding protein 1
MGI:2136825
Synonyms
MGC:7607
Feature Type
protein coding gene
Genetic Map
Chromosome 8
42.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:86841139-86885258 bp, - strand
From Ensembl annotation of GRCm38

  44120 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23703  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: N4BP1
Gene Tree: N4bp1

Human
homologs
N4BP1, Nedd4 binding protein 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9683
neXtProt AC: NX_O75113

Human Chr (Location): 16q12.1; chr16:48538726-48610214 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(25) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
N4bp1 interacts with 385 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cellular response to UV, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, ...
Component nucleolus, nucleus, ...
Function protein binding, RNA binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase n4bp1    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(7)
Other database
links
Ensembl Gene Model ENSMUSG00000031652 (Evidence)
Entrez Gene 80750 (Evidence)
DFCI TC1582674, TC1597762, TC1589686, TC1649318, TC1674918, TC1602381
DoTS DT.91592335, DT.94264078, DT.110894928, DT.101369711, DT.101155603
NIA Mouse Gene Index U030069
Consensus CDS Project CCDS52625.1
International Mouse Phenotyping Consortium Status N4bp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031652 Ensembl Gene Model | MGI Sequence Detail 44120 C57BL/6J ±  kb
transcript ENSMUST00000034074 Ensembl | MGI Sequence Detail 6469 Not Applicable 
polypeptide ENSMUSP00000034074 Ensembl | MGI Sequence Detail 893 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(230 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004088 K Homology domain, type 1
InterPro IPR021869 Ribonuclease Zc3h12a-like
Protein Ontology PR:000010937 NEDD4-binding protein 1
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173792 Bracken CP, et al., Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Res. 2011 Mar 22;
All references(35)
Other
accession IDs
MGI:2142573, MGI:2142863

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory