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Cwc22 Gene Detail
Summary
  • Symbol
    Cwc22
  • Name
    CWC22 spliceosome-associated protein
  • Synonyms
    MGC:7531
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136773
    NCBI Gene: 80744
Location & Maps
more
  • Sequence Map
    Chr2:77881159-77946375 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      65217 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 46.45 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CWC22, CWC22 spliceosome associated protein homolog
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CWC22, CWC22 spliceosome associated protein homolog
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EIF4GL, fSAPb, NCM
  • Links
    NCBI Gene ID: 57703
    neXtProt AC: NX_Q9HCG8

  • Chr Location
    2q31.3; chr2:179944876-180007297 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6048
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CWC22
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Gene trapped
    14
  • Targeted
    3
  • Genomic Mutations
    3 involving Cwc22
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013258 VEGA Gene Model | MGI Sequence Detail 65217 C57BL/6J ±  kb
transcript OTTMUST00000032030 VEGA | MGI Sequence Detail 3471 Not Applicable  
polypeptide OTTMUSP00000014253 VEGA | MGI Sequence Detail 908 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    392 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 9
Other
Accession IDs
less
MGI:2138849, MGI:2139123, MGI:3034792
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:214095 Osipovich AB, et al., Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development. 2014 Aug;141(15):2939-49

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory