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Pcdhb2 Gene Detail
Summary
  • Symbol
    Pcdhb2
  • Name
    protocadherin beta 2
  • Synonyms
    PcdhbB
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136735
    NCBI Gene: 93873
  • Gene Overview
    MyGene.info: PCDHB2
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:37294840-37297614 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.46 cM, cytoband B3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136735
protein coding gene Chr18:37294812-37297624 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024311
protein coding gene Chr18:35689148-35691961 (+)
A/J MGP_AJ_G0024278
protein coding gene Chr18:34482341-34485154 (+)
AKR/J MGP_AKRJ_G0024246
protein coding gene Chr18:35434428-35438218 (+)
BALB/cJ MGP_BALBcJ_G0024277
protein coding gene Chr18:34511285-34514098 (+)
C3H/HeJ MGP_C3HHeJ_G0024044
protein coding gene Chr18:35496266-35499080 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024719
protein coding gene Chr18:36985093-36987905 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022158
protein coding gene Chr18:34540885-34543687 (+)
CAST/EiJ MGP_CASTEiJ_G0023519
protein coding gene Chr18:35460143-35462955 (+)
CBA/J MGP_CBAJ_G0024013
protein coding gene Chr18:38074107-38076920 (+)
DBA/2J MGP_DBA2J_G0024143
protein coding gene Chr18:34072836-34075649 (+)
FVB/NJ MGP_FVBNJ_G0024110
protein coding gene Chr18:33792856-33795669 (+)
LP/J MGP_LPJ_G0024227
protein coding gene Chr18:35780284-35783097 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024140
protein coding gene Chr18:39339103-39341917 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024768
protein coding gene Chr18:35290321-35293134 (+)
PWK/PhJ MGP_PWKPhJ_G0023263
protein coding gene Chr18:34308638-34311565 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023069
protein coding gene Chr18:35537911-35540715 (+)
WSB/EiJ MGP_WSBEiJ_G0023582
protein coding gene Chr18:35190638-35193451 (+)



Homology
more
  • Human Ortholog
    PCDHB2, protocadherin beta 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PCDHB2, protocadherin beta 2
    Orthology source: HomoloGene
  • Synonyms
    PCDH-BETA2
  • Links
    NCBI Gene ID: 56133
    neXtProt AC: NX_Q9Y5E7
    UniProt: Q9Y5E7

  • Chr Location
    5q31.3; chr5:141094607-141097380 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93873 NCBI Gene Model | MGI Sequence Detail 2775 C57BL/6J ±  kb
transcript NM_053127 RefSeq | MGI Sequence Detail 2789 C57BL/6  
polypeptide NP_444357 RefSeq | MGI Sequence Detail 799 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:244163 Hasegawa S, et al., Distinct and Cooperative Functions for the Protocadherin-alpha, -beta and -gamma Clusters in Neuronal Survival and Axon Targeting. Front Mol Neurosci. 2016;9:155

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory