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Glp2r
Gene Detail
Symbol

Name
ID
Glp2r
glucagon-like peptide 2 receptor
MGI:2136733
Synonyms
9530092J08Rik, GLP-2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
41.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:67661502-67771153 bp, - strand
From VEGA annotation of GRCm38

  109652 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3132  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: G protein-coupled receptor, peptide hormone receptor type
Gene Tree: Glp2r

Human
homologs
Human Homolog GLP2R, glucagon-like peptide 2 receptor
NCBI Gene ID 9340
neXtProt AC  NX_O95838
Human Chr (Location)  17p13.3; chr17:9826064-9890952 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display defects in Paneth cell physiology, increased small bowel bacterial loads, and increased susceptibility to small bowel injury.
 
Interactions
Glp2r interacts with 248 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (27)    Tissues (4)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 27
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000005929 (Evidence)
Ensembl Gene ModelENSMUSG00000049928 (Evidence)
Entrez Gene93896 (Evidence)
UniGene118883
DFCITC1594188, TC1598616
DoTSDT.91377332, DT.94128158
NIA Mouse Gene IndexU032937
Consensus CDS ProjectCCDS24860.1
International Mouse Knockout Project StatusGlp2r
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005929 VEGA Gene Model | MGI Sequence Detail 109652 C57BL/6J ±  kb
transcript OTTMUST00000013197 VEGA | MGI Sequence Detail 4873 Not Applicable 
polypeptide OTTMUSP00000006124 VEGA | MGI Sequence Detail 512 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(1038 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001879 GPCR, family 2, extracellular hormone receptor domain
InterPro IPR017981 GPCR, family 2-like
InterPro IPR000832 GPCR, family 2, secretin-like
InterPro IPR017983 GPCR, family 2, secretin-like, conserved site
Protein Ontology PR:000008041 glucagon-like peptide 2 receptor
References
(Earliest) J:69966 Lovshin J, et al., Glucagon-like peptide (GLP)-2 action in the murine central nervous system is enhanced by elimination of GLP-1 receptor signaling. J Biol Chem. 2001 Jun 15;276(24):21489-99
(Latest) J:199234 Shi X, et al., Central GLP-2 Enhances Hepatic Insulin Sensitivity via Activating PI3K Signaling in POMC Neurons. Cell Metab. 2013 Jul 2;18(1):86-98
All references(31)
Other
accession IDs
MGI:2441752

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory