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Ddx49 Gene Detail
Summary
  • Symbol
    Ddx49
  • Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
  • Synonyms
    R27090_2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136689
    NCBI Gene: 234374
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70292866-70302489 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136689
protein coding gene Chr8:70292866-70302511 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033699
protein coding gene Chr8:70555943-70566013 (-)
A/J MGP_AJ_G0033682
protein coding gene Chr8:67686525-67696384 (-)
AKR/J MGP_AKRJ_G0033607
protein coding gene Chr8:69613574-69624594 (-)
BALB/cJ MGP_BALBcJ_G0033678
protein coding gene Chr8:67907960-67917543 (-)
C3H/HeJ MGP_C3HHeJ_G0033388
protein coding gene Chr8:70258641-70268678 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034195
protein coding gene Chr8:73226185-73237071 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031139
protein coding gene Chr8:62501836-62510836 (-)
CAST/EiJ MGP_CASTEiJ_G0032713
protein coding gene Chr8:69741607-69751197 (-)
CBA/J MGP_CBAJ_G0033366
protein coding gene Chr8:75848630-75858209 (-)
DBA/2J MGP_DBA2J_G0033520
protein coding gene Chr8:67407562-67417359 (-)
FVB/NJ MGP_FVBNJ_G0033461
protein coding gene Chr8:66514495-66524731 (-)
LP/J MGP_LPJ_G0033607
protein coding gene Chr8:70581928-70591541 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033504
protein coding gene Chr8:78520138-78532511 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034213
protein coding gene Chr8:69799164-69808991 (-)
PWK/PhJ MGP_PWKPhJ_G0032421
protein coding gene Chr8:66701715-66711561 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032257
protein coding gene Chr8:68765875-68776302 (-)
WSB/EiJ MGP_WSBEiJ_G0032828
protein coding gene Chr8:70157320-70168149 (-)



Homology
more
  • Human Ortholog
    DDX49, DEAD-box helicase 49
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DDX49, DEAD-box helicase 49
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Dbp8, R27090_2
  • Links
    NCBI Gene ID: 54555
    neXtProt AC: NX_Q9Y6V7
    UniProt: Q9Y6V7

  • Chr Location
    19p13.11; chr19:18919675-18928633 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41308
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DDX49
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057788 Ensembl Gene Model | MGI Sequence Detail 9624 C57BL/6J ±  kb
transcript ENSMUST00000008004 Ensembl | MGI Sequence Detail 2137 Not Applicable  
polypeptide ENSMUSP00000008004 Ensembl | MGI Sequence Detail 480 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 8

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:69829 Clarke D, et al., Comparative analysis of human 19p12-13 region in Fugu and mouse. Mamm Genome. 2001 Jun;12(6):478-83
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory