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Glce Gene Detail
Summary
  • Symbol
    Glce
  • Name
    glucuronyl C5-epimerase
  • Synonyms
    1110017N23Rik, C130034A12Rik, heparan sulfate-glucuronic acid C5-epimerase, Hsepi
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136405
    NCBI Gene: 93683
  • Gene Overview
    MyGene.info: GLCE
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:62057248-62122655 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 33.56 cM, cytoband C-D
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136405
protein coding gene Chr9:62057248-62122719 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034918
protein coding gene Chr9:61571833-61642689 (-)
A/J MGP_AJ_G0034898
protein coding gene Chr9:59554357-59620431 (-)
AKR/J MGP_AKRJ_G0034828
protein coding gene Chr9:60927546-60994895 (-)
BALB/cJ MGP_BALBcJ_G0034891
protein coding gene Chr9:59275529-59343220 (-)
C3H/HeJ MGP_C3HHeJ_G0034601
protein coding gene Chr9:61429483-61499540 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035410
protein coding gene Chr9:63247620-63314671 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032321
protein coding gene Chr9:59232281-59293144 (-)
CAST/EiJ MGP_CASTEiJ_G0033922
protein coding gene Chr9:61554476-61621754 (-)
CBA/J MGP_CBAJ_G0034572
protein coding gene Chr9:65426841-65491805 (-)
DBA/2J MGP_DBA2J_G0034731
protein coding gene Chr9:59355184-59421382 (-)
FVB/NJ MGP_FVBNJ_G0034673
protein coding gene Chr9:58639485-58704708 (-)
LP/J MGP_LPJ_G0034814
protein coding gene Chr9:61852229-61916981 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034716
protein coding gene Chr9:66834545-66905543 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035432
protein coding gene Chr9:60997047-61065020 (-)
PWK/PhJ MGP_PWKPhJ_G0033626
protein coding gene Chr9:59469035-59535563 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033459
protein coding gene Chr9:61289169-61359259 (-)
WSB/EiJ MGP_WSBEiJ_G0034035
protein coding gene Chr9:60913093-60979703 (-)



Homology
more
  • Human Ortholog
    GLCE, glucuronic acid epimerase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GLCE, glucuronic acid epimerase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSEPI
  • Links
    NCBI Gene ID: 26035
    neXtProt AC: NX_O94923
    UniProt: O94923

  • Chr Location
    15q23; chr15:69160555-69272209 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14111
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GLCE
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    1 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutant mice die immediately after birth showing severe developmental defects including renal agenesis, lung abnormalities, and skeletal malformations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032252 Ensembl Gene Model | MGI Sequence Detail 65408 C57BL/6J ±  kb
    transcript ENSMUST00000185675 Ensembl | MGI Sequence Detail 4850 Not Applicable  
    polypeptide ENSMUSP00000139949 Ensembl | MGI Sequence Detail 618 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1922030, MGI:2143115, MGI:2443854
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 4
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:244516 Sabik OL, et al., Genetic Dissection of a QTL Affecting Bone Geometry. G3 (Bethesda). 2017 Mar 10;7(3):865-870

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory