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Ice2 Gene Detail
Summary
  • Symbol
    Ice2
  • Name
    interactor of little elongation complex ELL subunit 2
  • Synonyms
    B230343B06Rik, Narg2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135947
    NCBI Gene: 93697
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:69397906-69433122 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 38.58 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    211 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135947
protein coding gene Chr9:69397639-69433122 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034991
protein coding gene Chr9:69388713-69423280 (+)
A/J MGP_AJ_G0034971
protein coding gene Chr9:67005066-67040318 (+)
AKR/J MGP_AKRJ_G0034901
protein coding gene Chr9:68592450-68629574 (+)
BALB/cJ MGP_BALBcJ_G0034964
protein coding gene Chr9:66733143-66767684 (+)
C3H/HeJ MGP_C3HHeJ_G0034673
protein coding gene Chr9:69101273-69136509 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035483
protein coding gene Chr9:71244356-71284127 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032394
protein coding gene Chr9:66581316-66615603 (+)
CAST/EiJ MGP_CASTEiJ_G0033995
protein coding gene Chr9:69349955-69388011 (+)
CBA/J MGP_CBAJ_G0034645
protein coding gene Chr9:73747785-73787700 (+)
DBA/2J MGP_DBA2J_G0034804
protein coding gene Chr9:66760096-66795237 (+)
FVB/NJ MGP_FVBNJ_G0034746
protein coding gene Chr9:66075220-66110647 (+)
LP/J MGP_LPJ_G0034886
protein coding gene Chr9:69653843-69689054 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034788
protein coding gene Chr9:74864160-74898804 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035505
protein coding gene Chr9:68731286-68765816 (+)
PWK/PhJ MGP_PWKPhJ_G0033699
protein coding gene Chr9:66971958-67007754 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033532
protein coding gene Chr9:69032277-69072009 (+)
WSB/EiJ MGP_WSBEiJ_G0034107
protein coding gene Chr9:68623586-68660263 (+)



Homology
more
  • Human Ortholog
    ICE2, interactor of little elongation complex ELL subunit 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ICE2, interactor of little elongation complex ELL subunit 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BRCC1, NARG2
  • Links
    NCBI Gene ID: 79664
    neXtProt AC: NX_Q659A1
    UniProt: Q659A1

  • Chr Location
    15q22.2; chr15:60419609-60479160 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11618
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ICE2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032235 Ensembl Gene Model | MGI Sequence Detail 35217 C57BL/6J ±  kb
transcript ENSMUST00000034761 Ensembl | MGI Sequence Detail 4169 Not Applicable  
polypeptide ENSMUSP00000034761 Ensembl | MGI Sequence Detail 988 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    cDNA 48

    Microarray probesets 5
Other
Accession IDs
less
MGI:2443085
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:68988 Yamamoto M, et al., Murine equivalent of the human histo-blood group ABO gene is a cis-AB gene and encodes a glycosyltransferase with both A and B transferase activity. J Biol Chem. 2001 Apr 27;276(17):13701-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory