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Lce3c Gene Detail
Summary
  • Symbol
    Lce3c
  • Name
    late cornified envelope 3C
  • Synonyms
    2300007B01Rik, Eig3, Sprrl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135932
    NCBI Gene: 94060
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92944486-92945730 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135932
protein coding gene Chr3:92944486-92945733 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027524
protein coding gene Chr3:93422249-93423930 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0027456
protein coding gene Chr3:92601263-92602510 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0027237
protein coding gene Chr3:92816266-92817513 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027941
protein coding gene Chr3:96982203-96984038 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020179
protein coding gene Chr15:84277176-84277410 (+)
CAST/EiJ MGP_CASTEiJ_G0026686
protein coding gene Chr3:92253344-92253877 (+)
CBA/J MGP_CBAJ_G0027213
protein coding gene Chr3:100332922-100334113 (+)
DBA/2J MGP_DBA2J_G0027351
protein coding gene Chr3:89802045-89802906 (+)
FVB/NJ MGP_FVBNJ_G0027318
protein coding gene Chr3:87972865-87974056 (+)
LP/J MGP_LPJ_G0027458
protein coding gene Chr3:94658276-94659523 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027345
protein coding gene Chr3:106610829-106611342 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0026414
protein coding gene Chr3:89730561-89732175 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0026767
protein coding gene Chr3:92713998-92724679 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Lce3c
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94060 NCBI Gene Model | MGI Sequence Detail 1245 C57BL/6J ±  kb
transcript NM_033175 RefSeq | MGI Sequence Detail 564 Not Specified  
polypeptide NP_149410 RefSeq | MGI Sequence Detail 98 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR028205 Late cornified envelope protein
    IPR026075 Small proline-rich protein/late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1916717, MGI:2139932
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:200244 Roth W, et al., Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J Cell Sci. 2012 Nov 15;125(Pt 22):5269-79

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory