About   Help   FAQ
Immp2l Gene Detail
Summary
  • Symbol
    Immp2l
  • Name
    IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
  • Synonyms
    IMP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135611
    NCBI Gene: 93757
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:41024090-41955588 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 18.69 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6324 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135611
protein coding gene Chr12:41024090-41955588 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019707
protein coding gene Chr12:39475713-40461675 (+)
A/J MGP_AJ_G0019672
protein coding gene Chr12:38172459-39073302 (+)
AKR/J MGP_AKRJ_G0019643
protein coding gene Chr12:39335380-40286703 (+)
BALB/cJ MGP_BALBcJ_G0019650
protein coding gene Chr12:38389184-39327288 (+)
C3H/HeJ MGP_C3HHeJ_G0019454
protein coding gene Chr12:39263129-40243786 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020097
protein coding gene Chr12:40634889-41610962 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017722
protein coding gene Chr12:37287998-38167793 (+)
CAST/EiJ MGP_CASTEiJ_G0019007
protein coding gene Chr12:34448864-35418622 (+)
CBA/J MGP_CBAJ_G0019426
protein coding gene Chr12:42016021-43061556 (+)
DBA/2J MGP_DBA2J_G0019539
protein coding gene Chr12:38018180-38946129 (+)
FVB/NJ MGP_FVBNJ_G0019528
protein coding gene Chr12:37645850-38536809 (+)
LP/J MGP_LPJ_G0019609
protein coding gene Chr12:39469746-40422100 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019564
protein coding gene Chr12:42162705-43294965 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020137
protein coding gene Chr12:38887677-39850724 (+)
PWK/PhJ MGP_PWKPhJ_G0018774
protein coding gene Chr12:32707222-33635554 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018564
protein coding gene Chr12:33558862-34498045 (+)
WSB/EiJ MGP_WSBEiJ_G0019057
protein coding gene Chr12:39207248-40179686 (+)



Homology
more
  • Human Ortholog
    IMMP2L, inner mitochondrial membrane peptidase subunit 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IMMP2L, inner mitochondrial membrane peptidase subunit 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IMMP2L-IT1, IMP2, IMP2-LIKE
  • Links
    NCBI Gene ID: 83943
    neXtProt AC: NX_Q96T52
    UniProt: Q96T52

  • Chr Location
    7q31.1; chr7:110662645-111562531 (-)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 3 alleles in 3 genetic backgrounds
    8 phenotypes from multigenic genotypes
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption exhibit reduced fertility, abnormal cellular respiration, and decreased body weight.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93757 NCBI Gene Model | MGI Sequence Detail 931499 C57BL/6J ±  kb
transcript NM_053122 RefSeq | MGI Sequence Detail 1163 C57BL/6  
polypeptide Q8BPT6 UniProt | EBI | MGI Sequence Detail 175 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144909, MGI:2153982
References
more
  • Summaries
    All 57
    Diseases 1
    Gene Ontology 9
    Phenotypes 29
  • Earliest
    J:31937 Newberg MH, et al., Importance of MHC class 1 alpha2 and alpha3 domains in the recognition of self and non-self MHC molecules. J Immunol. 1996 Apr 1;156(7):2473-80
  • Latest
    J:253473 Goodwin LO, et al., Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis. bioRxiv. 2017 Dec 18;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory