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Dync1li1
Gene Detail
Symbol

Name
ID
Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
MGI:2135610
Synonyms
1110053F02Rik, Dnclic1, LIC-1, MGC:32416
Feature Type
protein coding gene
Genetic Map
Chromosome 9
64.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:114688831-114723788 bp, + strand
From NCBI annotation of GRCm38

  34958 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9403  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DYNC1LI1
Gene Tree: Dync1li1

Human
homologs
DYNC1LI1, dynein, cytoplasmic 1, light intermediate chain 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51143
neXtProt AC: NX_Q9Y6G9

Human Synonyms: DNCLI1, LIC1

Human Chr (Location): 3p22.3; chr3:32525971-32570874 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(33) : Chemically induced (ENU)(1) Gene trapped(30) Targeted(2)
Incidental mutations (data from APF , CvDC )
 
Mice homozygous for an ENU-induced allele exhibit increased anxiety-related response, increased dendrite length, increased neuron migration, and decreased lysosome trafficking.
 
Interactions
Dync1li1 interacts with 189 markers (Mir7-1, Mir17, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cell cycle, cell division, ...
Component centrosome, chromosome, ...
Function ATP binding, microtubule motor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(83)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dync1li1 ; ZFIN dync1li1    NEW 
Molecular
reagents
All nucleic(83) cDNA(83)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000032435 (Evidence)
Entrez Gene 235661 (Evidence)
UniGene 128627
DFCI TC1620571, TC1604192, TC1575742, TC1779797, TC1707735
DoTS DT.110641546, DT.101380788, DT.55100766
NIA Mouse Gene Index U011105
Consensus CDS Project CCDS23595.1
International Mouse Phenotyping Consortium Status Dync1li1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 235661 NCBI Gene Model | MGI Sequence Detail 34958 C57BL/6J ±  kb
transcript NM_146229 RefSeq | MGI Sequence Detail 2046 C57BL/6 
polypeptide Q8R1Q8 UniProt | EBI | MGI Sequence Detail 523 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(139 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008467 Dynein 1 light intermediate chain
InterPro IPR022780 Dynein family light intermediate chain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000006773 cytoplasmic dynein 1 light intermediate chain 1
Graphical View of Protein Domain Structure
References
(Earliest) J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:1916070

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory