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Lin7a Gene Detail
Summary
  • Symbol
    Lin7a
  • Name
    lin-7 homolog A (C. elegans)
  • Synonyms
    LIN-7A, MALS-1, TIP-33, Veli
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135609
    NCBI Gene: 108030
  • Gene Overview
    MyGene.info: LIN7A
Location & Maps
more
  • Sequence Map
    Chr10:107271843-107425143 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      153301 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 55.83 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    LIN7A, lin-7 homolog A, crumbs cell polarity complex component
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LIN7A, lin-7 homolog A, crumbs cell polarity complex component
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LIN7, LIN-7A, MALS-1, TIP-33, VELI1
  • Links
    NCBI Gene ID: 8825
    neXtProt AC: NX_O14910

  • Chr Location
    12q21; chr12:80792520-80937923 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotypes from multigenic genotypes
    9 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Lin7a
  • Incidental Mutations
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019906 Ensembl Gene Model | MGI Sequence Detail 153301 C57BL/6J ±  kb
transcript ENSMUST00000020057 Ensembl | MGI Sequence Detail 5875 Not Applicable  
polypeptide ENSMUSP00000020057 Ensembl | MGI Sequence Detail 233 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    658 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 7
Other
Accession IDs
less
MGI:2143687
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 10
    Phenotypes 9
  • Earliest
    J:62660 Setou M, et al., Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science. 2000 Jun 9;288(5472):1796-802
  • Latest
    J:202837 Rowton M, et al., Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis. Dev Dyn. 2013 Nov;242(11):1332-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory