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Clec2d
Gene Detail
 Symbol
Name
ID
Clec2d
C-type lectin domain family 2, member d
MGI:2135589
Synonyms Clrb, Clr-b, Ocil
Feature Type protein coding gene
Genetic Map
Chromosome 6
63.16 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:129180615-129186534 bp, + strand
From VEGA annotation of GRCm38

  5920 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136309  Vertebrate Homology Class
3 mouse

Protein SuperFamily: early activation antigen CD69
Gene Tree: Clec2d

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Enhanced osteoclastic activity in the bone of homozygous null mice leads to osteopenia and high serum calcium levels.
 
Interactions
Clec2d interacts with 84 markers (Mir29a, Mir29b-1, Mir29b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cellular defense response, negative regulation of osteoclast differentiation, ...
Component external side of plasma membrane, integral component of membrane, ...
Function carbohydrate binding, natural killer cell lectin-like receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (75)    Tissues (35)    Images (3)
Theiler Stages: 23, 27, 28
Assay TypeResults
Immunohistochemistry 34
RNA in situ 33
Northern blot 8
cDNA source data(16)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000029144 (Evidence)
Ensembl Gene ModelENSMUSG00000030157 (Evidence)
Entrez Gene93694 (Evidence)
UniGene197536
DFCITC1585351
DoTSDT.489636
Consensus CDS ProjectCCDS20581.1
International Mouse Knockout Project StatusClec2d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029144 VEGA Gene Model | MGI Sequence Detail 5920 C57BL/6J ±  kb
transcript OTTMUST00000072287 VEGA | MGI Sequence Detail 1213 Not Applicable 
polypeptide OTTMUSP00000037157 VEGA | MGI Sequence Detail 207 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
Protein Ontology PR:000005566 C-type lectin domain family 2 member D
References (Earliest) J:69269 Zhou H, et al., A novel osteoblast-derived C-type lectin that inhibits osteoclast formation. J Biol Chem. 2001 May 4;276(18):14916-23
(Latest) J:178114 Pei L, et al., Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome. Nat Med. 2011;17(11):1466-72
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory