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Ifitm5
Gene Detail
Symbol

Name
ID
Ifitm5
interferon induced transmembrane protein 5
MGI:1934923
Synonyms
1110003J06Rik, Bril, fragilis4, Hrmp1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
86.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:140948963-140950239 bp, - strand
From Ensembl annotation of GRCm38

  1277 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14210  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog

Protein SuperFamily: interferon-induced transmembrane protein
Gene Tree: Ifitm5

Human
homologs
Human Homolog IFITM5, interferon induced transmembrane protein 5
NCBI Gene ID 387733
neXtProt AC  NX_A6NNB3
Human Synonyms  BRIL, DSPA1, fragilis4, Hrmp1, OI5
Human Chr (Location)  11p15.5; chr11:298200-299526 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human IFITM5
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Targeted(4)
Genomic Mutations involving Ifitm5 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ifitm5 interacts with 40 markers (Mir133a-1, Mir133a-2, Mir138-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process bone mineralization, bone morphogenesis, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (11)    Tissues (11)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 6
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000025489 (Evidence)
Entrez Gene73835 (Evidence)
UniGene389989
DFCITC1584568
DoTSDT.489487, DT.94353137
NIA Mouse Gene IndexU029438
Consensus CDS ProjectCCDS21993.1
International Mouse Knockout Project StatusIfitm5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025489 Ensembl Gene Model | MGI Sequence Detail 1277 C57BL/6J ±  kb
transcript ENSMUST00000026562 Ensembl | MGI Sequence Detail 708 Not Applicable 
polypeptide ENSMUSP00000026562 Ensembl | MGI Sequence Detail 134 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(51 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007593 Interferon-induced transmembrane protein
Protein Ontology PR:000032403 interferon-induced transmembrane protein 5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:1921085, MGI:2142220

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory