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Rnf111
Gene Detail
Symbol

Name
ID
Rnf111
ring finger 111
MGI:1934919
Synonyms
Arkadia
Feature Type
protein coding gene
Genetic Map
Chromosome 9
39.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:70425429-70503725 bp, - strand
From Ensembl annotation of GRCm38

  78297 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9741  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rnf111

Human
homologs
Human Homolog RNF111, ring finger protein 111
NCBI Gene ID 54778
neXtProt AC  NX_Q6ZNA4
Human Synonyms  ARK
Human Chr (Location)  15q21; chr15:58987666-59097419 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(471) : Gene trapped(469) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mutations in this gene cause developmental defects in extraembryonic lineages, resulting in arrested development and lethality around midgestation.
 
Interactions
Rnf111 interacts with 395 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (58)    Tissues (56)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 54
RT-PCR 4
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(17) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000032217 (Evidence)
Entrez Gene93836 (Evidence)
DFCITC1588550, TC1576908
DoTSDT.101380058, DT.101351916, DT.101207935, DT.489504, DT.97358670, DT.91386243, DT.101271084
NIA Mouse Gene IndexU031056, U359308
EC6.3.2.-
Consensus CDS ProjectCCDS23321.1
International Mouse Knockout Project StatusRnf111
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032217 Ensembl Gene Model | MGI Sequence Detail 78297 C57BL/6J ±  kb
transcript ENSMUST00000034739 Ensembl | MGI Sequence Detail 4880 Not Applicable 
polypeptide ENSMUSP00000034739 Ensembl | MGI Sequence Detail 989 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(26) UniProt(1)
Polymorphisms
SNPs within 2kb(180 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000014067 E3 ubiquitin-protein ligase Arkadia
References
(Earliest) J:68833 Episkopou V, et al., Induction of the mammalian node requires Arkadia function in the extraembryonic lineages. Nature. 2001 Apr 12;410(6830):825-30
(Latest) J:204028 Erker Y, et al., Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation. Mol Cell Biol. 2013 Jun;33(11):2163-77
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory