About   Help   FAQ
Pi15 Gene Detail
Summary
  • Symbol
    Pi15
  • Name
    peptidase inhibitor 15
  • Synonyms
    P24TI, P25TI, SugarCrisp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934659
    NCBI Gene: 94227
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:17601901-17630939 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 5.32 cM, cytoband A4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934659
protein coding gene Chr1:17601901-17630939 (.)
129S1/SvImJ MGP_129S1SvImJ_G0015862
protein coding gene Chr1:15149272-15186648 (+)
A/J MGP_AJ_G0015843
protein coding gene Chr1:14952005-14981051 (+)
AKR/J MGP_AKRJ_G0015802
protein coding gene Chr1:14954509-14985119 (+)
BALB/cJ MGP_BALBcJ_G0015799
protein coding gene Chr1:14656689-14686031 (+)
C3H/HeJ MGP_C3HHeJ_G0015633
protein coding gene Chr1:15009289-15049026 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016253
protein coding gene Chr1:15837768-15868047 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013974
protein coding gene Chr1:13442499-13471979 (+)
CAST/EiJ MGP_CASTEiJ_G0015214
protein coding gene Chr1:15064326-15094380 (+)
CBA/J MGP_CBAJ_G0015606
protein coding gene Chr1:16169161-16208394 (+)
DBA/2J MGP_DBA2J_G0015705
protein coding gene Chr1:14533396-14565019 (+)
FVB/NJ MGP_FVBNJ_G0015710
protein coding gene Chr1:14301957-14330120 (+)
LP/J MGP_LPJ_G0015777
protein coding gene Chr1:15348176-15377146 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015729
protein coding gene Chr1:16849397-16884158 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016300
protein coding gene Chr1:14944527-14975402 (+)
PWK/PhJ MGP_PWKPhJ_G0014998
protein coding gene Chr1:14283692-14315092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014779
protein coding gene Chr1:15055432-15087094 (+)
WSB/EiJ MGP_WSBEiJ_G0015277
protein coding gene Chr1:14882733-14913751 (+)



Homology
more
  • Human Ortholog
    PI15, peptidase inhibitor 15
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PI15, peptidase inhibitor 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CRISP8, P24TI, P25TI
  • Links
    NCBI Gene ID: 51050
    neXtProt AC: NX_O43692
    UniProt: O43692

  • Chr Location
    8q21.13; chr8:74824537-74855044 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 22935
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PI15
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 94227 NCBI Gene Model | MGI Sequence Detail 29039 C57BL/6J ±  kb
transcript NM_053191 RefSeq | MGI Sequence Detail 6946 C57BL/6  
polypeptide Q8BS03 UniProt | EBI | MGI Sequence Detail 258 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR018244 Allergen V5/Tpx-1-related, conserved site
    IPR014044 CAP domain
    IPR035940 CAP superfamily
    IPR001283 Cysteine-rich secretory protein, allergen V5/Tpx-1-related
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:69449 Smith DM, et al., Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo. Mech Dev. 2001;102(1-2):223-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory