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Pi15 Gene Detail
Summary
  • Symbol
    Pi15
  • Name
    peptidase inhibitor 15
  • Synonyms
    P24TI, P25TI, SugarCrisp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934659
    NCBI Gene: 94227
Location & Maps
more
  • Sequence Map
    Chr1:17601901-17630939 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      29039 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 5.32 cM, cytoband A4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PI15, peptidase inhibitor 15
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PI15, peptidase inhibitor 15
    Orthology source: HomoloGene
  • Synonyms
    CRISP8, P24TI, P25TI
  • Links
    NCBI Gene ID: 51050
    neXtProt AC: NX_O43692

  • Chr Location
    8q21.11; chr8:74824469-74855044 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 22935
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: PI15
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048206 VEGA Gene Model | MGI Sequence Detail 29039 C57BL/6J ±  kb
transcript OTTMUST00000123771 VEGA | MGI Sequence Detail 6923 Not Applicable  
polypeptide OTTMUSP00000067503 VEGA | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    260 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR018244 Allergen V5/Tpx-1-related, conserved site
    IPR014044 CAP domain
    IPR001283 Cysteine-rich secretory protein, allergen V5/Tpx-1-related
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:69449 Smith DM, et al., Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo. Mech Dev. 2001;102(1-2):223-6
  • Latest
    J:106710 Takemoto M, et al., Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J. 2006 Mar 8;25(5):1160-74

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory