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Sucnr1
Gene Detail
Symbol

Name
ID
Sucnr1
succinate receptor 1
MGI:1934135
Synonyms
Gpr91
Feature Type
protein coding gene
Genetic Map
Chromosome 3
29.17 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:60081869-60087566 bp, + strand
From VEGA annotation of GRCm38

  5698 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 5 western clawed frog

HCOP human homology predictions: SUCNR1
Protein SuperFamily: succinate receptor 1
Gene Tree: Sucnr1

Human
homologs
SUCNR1, succinate receptor 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 56670
neXtProt AC: NX_Q9BXA5

Human Synonyms: GPR91

Human Chr (Location): 3q25.1; chr3:151873643-151882088 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a knockout allele exhibit decreased renin plasma and kidney levels upon high-glucose stimulation in a diabetic or non-diabetic model.
 
Interactions
Sucnr1 interacts with 97 markers (Mir18b, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(4)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100494514    NEW 
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000051954 (Evidence)
Ensembl Gene Model ENSMUSG00000027762 (Evidence)
Entrez Gene 84112 (Evidence)
UniGene 125110
DFCI TC1585971
DoTS DT.55148851
NIA Mouse Gene Index U003277
Consensus CDS Project CCDS38442.1
International Mouse Phenotyping Consortium Status Sucnr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051954 VEGA Gene Model | MGI Sequence Detail 5698 C57BL/6J ±  kb
transcript OTTMUST00000130746 VEGA | MGI Sequence Detail 1571 Not Applicable 
polypeptide OTTMUSP00000070035 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001556 succinate receptor 1
References
(Earliest) J:68335 Wittenberger T, et al., An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. J Mol Biol. 2001 Mar 30;307(3):799-813
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory