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Sucnr1
Gene Detail
 Symbol
Name
ID
Sucnr1
succinate receptor 1
MGI:1934135
Synonyms Gpr91
Feature Type protein coding gene
Genetic Map
Chromosome 3
29.17 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:60081869-60087566 bp, + strand
From NCBI annotation of GRCm38

  5698 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 5 western clawed frog

Protein SuperFamily: succinate receptor 1
Gene Tree: Sucnr1

Human
homologs
Human Homolog SUCNR1, succinate receptor 1
NCBI Gene ID 56670
neXtProt AC  NX_Q9BXA5
Human Synonyms  GPR91
Human Chr (Location)  3q25.1; chr3:151873643-151882088 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from APF )
 
Mice homozygous for a knockout allele exhibit decreased renin plasma and kidney levels upon high-glucose stimulation in a diabetic or non-diabetic model.
 
Interactions
Sucnr1 interacts with 97 markers (Mir18b, Mir22, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process G-protein coupled receptor signaling pathway, signal transduction
Component extracellular vesicular exosome, integral component of membrane, ...
Function G-protein coupled receptor activity, signal transducer activity
External Resources: FuncBase
Expression
cDNA source data(4)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000027762 (Evidence)
Entrez Gene84112 (Evidence)
UniGene125110
DFCITC1585971
DoTSDT.55148851
NIA Mouse Gene IndexU003277
Consensus CDS ProjectCCDS38442.1
International Mouse Knockout Project StatusSucnr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 84112 NCBI Gene Model | MGI Sequence Detail 5698 C57BL/6J ±  kb
transcript NM_032400 RefSeq | MGI Sequence Detail 1571 C57BL/6 
polypeptide Q99MT6 UniProt | EBI | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001556 succinate receptor 1
Graphical View of Protein Domain Structure
References (Earliest) J:68335 Wittenberger T, et al., An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. J Mol Biol. 2001 Mar 30;307(3):799-813
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory