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Dleu2 Gene Detail
Summary
  • Symbol
    Dleu2
  • Name
    deleted in lymphocytic leukemia, 2
  • Synonyms
    1810047A16Rik, 4932411A06Rik, 7730401J12Rik, Alt1, Gm9069, Leu2
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1934030
    NCBI Gene: 668253
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:61840288-61919822 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 33.16 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    316 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934030
lncRNA gene Chr14:61840285-61919822 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015270
unclassified non-coding RNA gene Chr14:55989976-56080260 (-)
A/J MGP_AJ_G0015244
unclassified non-coding RNA gene Chr14:54770427-54851179 (-)
AKR/J MGP_AKRJ_G0015207
unclassified non-coding RNA gene Chr14:56719600-56809397 (-)
BALB/cJ MGP_BALBcJ_G0015208
unclassified non-coding RNA gene Chr14:54726112-54806297 (-)
C3H/HeJ MGP_C3HHeJ_G0015032
unclassified non-coding RNA gene Chr14:56351702-56439590 (-)
C57BL/6NJ MGP_C57BL6NJ_G0015663
unclassified non-coding RNA gene Chr14:58717186-58803063 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013404
unclassified non-coding RNA gene Chr14:52743460-52821144 (-)
CAST/EiJ MGP_CASTEiJ_G0014583
unclassified non-coding RNA gene Chr14:52750935-52834699 (-)
CBA/J MGP_CBAJ_G0015012
unclassified non-coding RNA gene Chr14:60406949-60502895 (-)
DBA/2J MGP_DBA2J_G0015105
unclassified non-coding RNA gene Chr14:54426820-54517708 (-)
FVB/NJ MGP_FVBNJ_G0015113
unclassified non-coding RNA gene Chr14:53855054-53934389 (-)
LP/J MGP_LPJ_G0015186
unclassified non-coding RNA gene Chr14:57023901-57110911 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0015702
unclassified non-coding RNA gene Chr14:55869003-55953447 (-)
PWK/PhJ MGP_PWKPhJ_G0014375
unclassified non-coding RNA gene Chr14:51100592-51182534 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014162
unclassified non-coding RNA gene Chr14:51795846-51880484 (-)
WSB/EiJ MGP_WSBEiJ_G0014690
unclassified non-coding RNA gene Chr14:56188879-56270820 (-)



Homology
less
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    38
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    33
  • Targeted
    3
  • Genomic Mutations
    4 involving Dleu2
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000097589 Ensembl Gene Model | MGI Sequence Detail 79535 C57BL/6J ±  kb
transcript ENSMUST00000193208 Ensembl | MGI Sequence Detail 4098 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 23
    Genomic 1
    cDNA 21
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1353583, MGI:1917069, MGI:2145689, MGI:2441725, MGI:3779832
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Diseases 2
    Gene Ontology 1
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:317184 Chesi M, et al., Monosomic loss of MIR15A/MIR16-1 is a driver of multiple myeloma proliferation and disease progression. Blood Cancer Discov. 2020 Jul;1(1):68-81

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/28/2022
MGI 6.20
The Jackson Laboratory