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Ntng1 Gene Detail
Summary
  • Symbol
    Ntng1
  • Name
    netrin G1
  • Synonyms
    A930010C08Rik, Lmnt1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934028
    NCBI Gene: 80883
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:109687356-110051327 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 48.47 cM, cytoband G1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2820 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934028
 protein coding gene Chr3:109687356-110057291 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027795
 protein coding gene Chr3:111406921-111769604 (-)
A/J MGP_AJ_G0027755
 protein coding gene Chr3:107849872-108202798 (-)
AKR/J MGP_AKRJ_G0027720
 protein coding gene Chr3:110503586-110862241 (-)
BALB/cJ MGP_BALBcJ_G0027767
 protein coding gene Chr3:107557093-107915304 (-)
C3H/HeJ MGP_C3HHeJ_G0027497
 protein coding gene Chr3:110845559-111210014 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028211
 protein coding gene Chr3:115535329-115903577 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025549
 protein coding gene Chr3:103939794-104283667 (-)
CAST/EiJ MGP_CASTEiJ_G0026953
 protein coding gene Chr3:110264281-110621008 (-)
CBA/J MGP_CBAJ_G0027472
 protein coding gene Chr3:119497673-119899880 (-)
DBA/2J MGP_DBA2J_G0027614
 protein coding gene Chr3:107033881-107396750 (-)
FVB/NJ MGP_FVBNJ_G0027582
 protein coding gene Chr3:104895172-105242315 (-)
LP/J MGP_LPJ_G0027721
 protein coding gene Chr3:112841618-113216784 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027612
 protein coding gene Chr3:125514273-125908985 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028266
 protein coding gene Chr3:110097390-110460974 (-)
PWK/PhJ MGP_PWKPhJ_G0026679
 protein coding gene Chr3:106791347-107144400 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026499
 protein coding gene Chr3:108270864-108635386 (-)
WSB/EiJ MGP_WSBEiJ_G0027033
 protein coding gene Chr3:110641247-111014708 (-)



Homology
more
  • Human Ortholog
    NTNG1, netrin G1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NTNG1, netrin G1
  • Synonyms
    Lmnt1, NetG1, NetrinG1
  • Links
    NCBI Gene ID: 22854
    neXtProt AC: NX_Q9Y2I2
    UniProt: Q9Y2I2

  • Chr Location
    1p13.3; chr1:107140007-107484923 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    22 phenotype references
Mice homozygous for a null allele survive into adulthood with no major alterations in gross brain cytoarchitecture or axonal projection.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    821
  • Tissues
    50
  • cDNA Data
    14
  • Literature Summary
    39
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059857 Ensembl Gene Model | MGI Sequence Detail 363972 C57BL/6J ±  kb
transcript ENSMUST00000072596 Ensembl | MGI Sequence Detail 1620 Not Applicable  
polypeptide ENSMUSP00000072397 Ensembl | MGI Sequence Detail 539 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1925193, MGI:2139833
References
more
  • Summaries
    All 90
    Developmental Gene Expression 39
    Diseases 1
    Gene Ontology 10
    Phenotypes 22
  • Earliest
    J:64213 Nakashiba T, et al., Netrin-G1: a novel glycosyl phosphatidylinositol-linked mammalian netrin that is functionally divergent from classical netrins. J Neurosci. 2000 Sep 1;20(17):6540-50
  • Latest
    J:339312 Sinclair-Wilson A, et al., Plasticity of thalamocortical axons is regulated by serotonin levels modulated by preterm birth. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2301644120
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory