About   Help   FAQ
Dnaja3
Gene Detail
 Symbol
Name
ID
Dnaja3
DnaJ (Hsp40) homolog, subfamily A, member 3
MGI:1933786
Synonyms 1200003J13Rik, 1810053A11Rik, Tid-1
Feature Type protein coding gene
Genetic Map
Chromosome 16
2.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:4639989-4707695 bp, + strand
From VEGA annotation of GRCm38

  67707 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36170  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Dnaja3

Human
homologs
Human Homolog DNAJA3, DnaJ (Hsp40) homolog, subfamily A, member 3
NCBI Gene ID 9093
neXtProt AC  NX_Q96EY1
Human Synonyms  HCA57, hTID-1, TID1
Human Chr (Location)  16p13.3; chr16:4425805-4456775 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(8) Targeted(6)
Incidental mutations (data from APF )
 
Early embryonic development of homozygous null embryos is disrupted. Blastocysts develop and implant but die afterwards.
 
Interactions
Dnaja3 interacts with 164 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (65 annotations)
Process activation-induced cell death of T cells, activation of cysteine-type endopeptidase activity involved in apoptotic process, ...
Component actin filament, cell junction, ...
Function ATP binding, heat shock protein binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000024742 (Evidence)
Ensembl Gene ModelENSMUSG00000004069 (Evidence)
Entrez Gene83945 (Evidence)
DFCITC1572604, TC1588650, TC1598740, TC1648883, TC1674611
DoTSDT.534703, DT.101123151, DT.101311635, DT.101391197, DT.110719911, DT.55274535, DT.91447718, DT.94403828, DT.94403832, DT.94403870
NIA Mouse Gene IndexU016761
Consensus CDS ProjectCCDS27922.1, CCDS49748.1
International Mouse Knockout Project StatusDnaja3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024742 VEGA Gene Model | MGI Sequence Detail 67707 C57BL/6J ±  kb
transcript OTTMUST00000059741 VEGA | MGI Sequence Detail 2648 Not Applicable 
polypeptide OTTMUSP00000029081 VEGA | MGI Sequence Detail 480 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(206 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012724 Chaperone DnaJ
InterPro IPR002939 Chaperone DnaJ, C-terminal
InterPro IPR001623 DnaJ domain
InterPro IPR018253 DnaJ domain, conserved site
InterPro IPR001305 Heat shock protein DnaJ, cysteine-rich domain
InterPro IPR008971 HSP40/DnaJ peptide-binding
Protein Ontology PR:000006572 DnaJ homolog subfamily A member 3, mitochondrial
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(44)
Other
accession IDs
MGI:1914108, MGI:1919302, MGI:2146711

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory