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Smarcd2 Gene Detail
Summary
  • Symbol
    Smarcd2
  • Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
  • Synonyms
    Baf60b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933621
    NCBI Gene: 83796
  • Gene Overview
    MyGene.info: SMARCD2
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106263179-106272972 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933621
protein coding gene Chr11:106263171-106272991 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019301
protein coding gene Chr11:109553264-109563012 (-)
A/J MGP_AJ_G0019269
protein coding gene Chr11:104890085-104899827 (-)
AKR/J MGP_AKRJ_G0019238
protein coding gene Chr11:108017385-108027198 (-)
BALB/cJ MGP_BALBcJ_G0019243
protein coding gene Chr11:105298373-105308569 (-)
C3H/HeJ MGP_C3HHeJ_G0019052
protein coding gene Chr11:108306939-108316731 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019693
protein coding gene Chr11:112902708-112912536 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017317
protein coding gene Chr11:102167746-102177173 (-)
CAST/EiJ MGP_CASTEiJ_G0018605
protein coding gene Chr11:109362618-109372698 (-)
CBA/J MGP_CBAJ_G0019021
protein coding gene Chr11:117602836-117612632 (-)
DBA/2J MGP_DBA2J_G0019133
protein coding gene Chr11:104358066-104367863 (-)
FVB/NJ MGP_FVBNJ_G0019124
protein coding gene Chr11:103861754-103871783 (-)
LP/J MGP_LPJ_G0019203
protein coding gene Chr11:109994215-110006768 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019154
protein coding gene Chr11:116886922-116896716 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019730
protein coding gene Chr11:108510438-108521444 (-)
PWK/PhJ MGP_PWKPhJ_G0018370
protein coding gene Chr11:105455152-105465429 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018161
protein coding gene Chr11:108272834-108282375 (-)
WSB/EiJ MGP_WSBEiJ_G0018656
protein coding gene Chr11:108472384-108482559 (-)



Homology
more
  • Human Ortholog
    SMARCD2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SMARCD2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAF60B, CRACD2, PRO2451, Rsc6p, SGD2
  • Links
    NCBI Gene ID: 6603
    neXtProt AC: NX_Q92925
    UniProt: Q92925

  • Chr Location
    17q23.3; chr17:63832081-63842991 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000078619 Ensembl Gene Model | MGI Sequence Detail 9794 C57BL/6J ±  kb
    transcript ENSMUST00000021052 Ensembl | MGI Sequence Detail 2747 Not Applicable  
    polypeptide ENSMUSP00000021052 Ensembl | MGI Sequence Detail 531 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 213
      cDNA 211
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2144524
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 12
      Gene Ontology 5
      Phenotypes 8
    • Earliest
      J:156242 Olave I, et al., Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes Dev. 2002 Oct 1;16(19):2509-17
    • Latest
      J:264370 Sima J, et al., Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory