About   Help   FAQ
Smarcd2 Gene Detail
Summary
  • Symbol
    Smarcd2
  • Name
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
  • Synonyms
    Baf60b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933621
    NCBI Gene: 83796
  • Gene Overview
    MyGene.info: SMARCD2
Location & Maps
more
  • Sequence Map
    Chr11:106263179-106272972 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9794 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.89 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SMARCD2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SMARCD2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BAF60B, CRACD2, PRO2451, Rsc6p
  • Links
    NCBI Gene ID: 6603
    neXtProt AC: NX_Q92925

  • Chr Location
    17q23.3; chr17:63832081-63842991 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Gene trapped
    2
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003421 VEGA Gene Model | MGI Sequence Detail 9794 C57BL/6J ±  kb
transcript OTTMUST00000007203 VEGA | MGI Sequence Detail 2747 Not Applicable  
polypeptide OTTMUSP00000003464 VEGA | MGI Sequence Detail 531 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    12 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000015266 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
  • InterPro Domains
    IPR019835 SWIB domain
    IPR003121 SWIB/MDM2 domain
    IPR030090 SWI/SNF complex subunit BAF60B
Molecular
Reagents
less
  • All nucleic 212
    cDNA 210
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144524
References
more
  • Summaries
    All 33
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:156242 Olave I, et al., Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes Dev. 2002 Oct 1;16(19):2509-17
  • Latest
    J:229124 Guess MG, et al., miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. PLoS One. 2015;10(2):e0118229

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/12/2016
MGI 6.04
The Jackson Laboratory