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Slmap Gene Detail
Summary
  • Symbol
    Slmap
  • Name
    sarcolemma associated protein
  • Synonyms
    D330001L02Rik, mKIAA1601, Slap
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933549
    NCBI Gene: 83997
  • Gene Overview
    MyGene.info: SLMAP
Location & Maps
more
  • Sequence Map
    Chr14:26413168-26534931 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      121764 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLMAP, sarcolemma associated protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLMAP, sarcolemma associated protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SLAP
  • Links
    NCBI Gene ID: 7871
    neXtProt AC: NX_Q14BN4

  • Chr Location
    3p21.2-p14.3; chr3:57756221-57930003 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 31428
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SLMAP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    36
  • Gene trapped
    33
  • Targeted
    2
  • Transposon induced
    1
  • Incidental Mutations
Homozygous inactivation in this locus affects T cell development. Mice homozygous for a transposon induced allele exhibit cleft palate.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016367 VEGA Gene Model | MGI Sequence Detail 121764 C57BL/6J ±  kb
transcript OTTMUST00000039385 VEGA | MGI Sequence Detail 4508 Not Applicable  
polypeptide OTTMUSP00000017600 VEGA | MGI Sequence Detail 845 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    513 from dbSNP Build 142
Protein
Information
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  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000015244 sarcolemmal membrane-associated protein
  • InterPro Domains
    IPR000253 Forkhead-associated (FHA) domain
    IPR001363 Proteinase inhibitor I25C, fetuin, conserved site
    IPR030498 Sarcolemmal membrane-associated protein
    IPR008984 SMAD/FHA domain
Molecular
Reagents
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  • All nucleic 145
    cDNA 143
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:2442165
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:28203 Pandey A, et al., Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase. J Biol Chem. 1995 Aug 18;270(33):19201-4
  • Latest
    J:171727 Schlesinger J, et al., The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs. PLoS Genet. 2011 Feb;7(2):e1001313

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory