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Ifitm2 Gene Detail
Summary
  • Symbol
    Ifitm2
  • Name
    interferon induced transmembrane protein 2
  • Synonyms
    fragilis3, Ifitm3l, mil-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933382
    NCBI Gene: 80876
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140954839-140955961 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 86.18 cM, cytoband F5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933382
protein coding gene Chr7:140954837-140955987 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033203
protein coding gene Chr7:146092299-146093988 (-)
A/J MGP_AJ_G0033185
protein coding gene Chr7:141938735-141939857 (-)
AKR/J MGP_AKRJ_G0033117
protein coding gene Chr7:145829340-145830474 (-)
BALB/cJ MGP_BALBcJ_G0033186
protein coding gene Chr7:141666463-141667940 (-)
C3H/HeJ MGP_C3HHeJ_G0032900
protein coding gene Chr7:145586438-145588077 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033697
protein coding gene Chr7:151437715-151438837 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030670
protein coding gene Chr7:143149727-143150834 (-)
CAST/EiJ MGP_CASTEiJ_G0032230
protein coding gene Chr7:137886781-137889300 (-)
CBA/J MGP_CBAJ_G0032872
protein coding gene Chr7:156567008-156568448 (-)
DBA/2J MGP_DBA2J_G0033025
protein coding gene Chr7:139876782-139878385 (-)
FVB/NJ MGP_FVBNJ_G0032977
protein coding gene Chr7:139789454-139791488 (-)
LP/J MGP_LPJ_G0033119
protein coding gene Chr7:147596751-147599422 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033010
protein coding gene Chr7:157228854-157229976 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033717
protein coding gene Chr7:144813493-144814615 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0031781
protein coding gene Chr7:131629993-131633393 (-)
WSB/EiJ MGP_WSBEiJ_G0032341
protein coding gene Chr7:145735237-145736347 (-)



Homology
more
  • Human Ortholog
    IFITM2, interferon induced transmembrane protein 2
  • Vertebrate Orthologs
    5
  • Human Ortholog
    IFITM2, interferon induced transmembrane protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    1-8D, DSPA2c
  • Links
    NCBI Gene ID: 10581
    neXtProt AC: NX_Q01629
    UniProt: Q01629

  • Chr Location
    11p15.5; chr11:308107-309410 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 80876 NCBI Gene Model | MGI Sequence Detail 1123 C57BL/6J ±  kb
transcript NM_030694 RefSeq | MGI Sequence Detail 646 Not Specified  
polypeptide Q99J93 UniProt | EBI | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007593 CD225/Dispanin family
Molecular
Reagents
less
  • All nucleic 181
    cDNA 178
    Primer pair 3

    Microarray probesets 5
References
more
  • Summaries
    All 44
    Developmental Gene Expression 8
    Gene Ontology 9
    Phenotypes 10
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:264160 Patoine A, et al., The osteogenic cell surface marker BRIL/IFITM5 is dispensable for bone development and homeostasis in mice. PLoS One. 2017;12(9):e0184568

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory