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Gtf2a1
Gene Detail
 Symbol
Name
ID
Gtf2a1
general transcription factor II A, 1
MGI:1933277
Synonyms 19kDa, 37kDa, 6330549H03Rik, Tfiia1, TfIIAa/b
Feature Type protein coding gene
Genetic Map
Chromosome 12
45.02 cM, cytoband E
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:91555916-91590487 bp, - strand
From VEGA annotation of GRCm38

  34572 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56331  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: hypothetical protein, Caenorhabditis elegans K11D12.2 type
Gene Tree: Gtf2a1

Human
homologs
Human Homolog GTF2A1, general transcription factor IIA, 1, 19/37kDa
NCBI Gene ID 2957
neXtProt AC  NX_P52655
Human Synonyms  TF2A1, TFIIA, TFIIA-42, TFIIAL
Human Chr (Location)  14q31.1; chr14:81175452-81221231 (-)  GRCh38
Alleles
and
phenotypes
All alleles(72) : Gene trapped(66) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process regulation of transcription, DNA-templated, transcription, DNA-templated, ...
Component cytoplasm, nucleus, ...
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (94)    Tissues (66)    Images (22)
Theiler Stages: 1, 2, 3, 4, 5, 15, 17, 18, 19, 21, 23, 28
Assay TypeResults
RNA in situ 62
RT-PCR 32
cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(22) cDNA(19) Primer pair(3)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000035545 (Evidence)
Ensembl Gene ModelENSMUSG00000020962 (Evidence)
Entrez Gene83602 (Evidence)
DFCITC1584567, TC1590047, TC1598148, TC1616878
DoTSDT.101366357, DT.97370900
NIA Mouse Gene IndexU034229
Consensus CDS ProjectCCDS26089.1, CCDS49136.1
International Mouse Knockout Project StatusGtf2a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035545 VEGA Gene Model | MGI Sequence Detail 34572 C57BL/6J ±  kb
transcript OTTMUST00000091041 VEGA | MGI Sequence Detail 5410 Not Applicable 
polypeptide OTTMUSP00000050089 VEGA | MGI Sequence Detail 378 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(161 from dbSNP Build 137)    SNPs within 2kb including multiple locations(199)
Protein-related
information
ResourceIDDescription
InterPro IPR004855 Transcription factor IIA, alpha/beta subunit
InterPro IPR013028 Transcription factor IIA, alpha subunit, N-terminal
InterPro IPR009088 Transcription factor IIA, beta-barrel
InterPro IPR009083 Transcription factor IIA, helical
Protein Ontology PR:000008310 transcription initiation factor IIA subunit 1
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:205038 Oyama T, et al., Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. Dev Cell. 2013 Oct 28;27(2):188-200
All references(53)
Other
accession IDs
MGI:1915037, MGI:2144740, MGI:2144749, MGI:2144998

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory