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Tex11 Gene Detail
Summary
  • Symbol
    Tex11
  • Name
    testis expressed gene 11
  • Synonyms
    4930565P14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933237
    NCBI Gene: 83558
Location & Maps
more
  • Sequence Map
    ChrX:100838648-101059667 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      221020 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 43.72 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TEX11, testis expressed 11
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TEX11, testis expressed 11
    Orthology source: HomoloGene
  • Synonyms
    SPGFX2, TGC1, TSGA3
  • Links
    NCBI Gene ID: 56159
    neXtProt AC: NX_Q8IYF3

  • Chr Location
    Xq13.1; chrX:70525561-70908717 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 49962
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: TEX11
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human TEX11 associations

Human Disease Mouse Models
       Spermatogenic Failure, X-Linked, 2; SPGFX2   OMIM: 309120
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Gene trapped
    1
  • Targeted
    5
  • Incidental Mutations
    APF
Miche homozygous for a knockout allele exhibit abnormal male meiosis. Mice homozygous for a conditional knockout exhibit male infertility and reduced female fecundity due to abnormal meiosis following cre recombination.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018300 VEGA Gene Model | MGI Sequence Detail 221020 C57BL/6J ±  kb
transcript OTTMUST00000044216 VEGA | MGI Sequence Detail 3278 Not Applicable  
polypeptide OTTMUSP00000019877 VEGA | MGI Sequence Detail 947 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    393 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000016249 testis-expressed sequence 11 protein
  • InterPro Domains
    IPR013940 Meiosis specific protein Spo22/ZIP4/TEX11
    IPR011990 Tetratricopeptide-like helical domain
Molecular
Reagents
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  • All nucleic 11
    cDNA 9
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
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MGI:2148032, MGI:2442304
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:68614 Wang PJ, et al., An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr;27(4):422-6
  • Latest
    J:196206 Reynolds A, et al., RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis. Nat Genet. 2013 Mar;45(3):269-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory