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Tdrd1
Gene Detail
 Symbol
Name
ID
Tdrd1
tudor domain containing 1
MGI:1933218
Synonyms MTR-1
Feature Type protein coding gene
Genetic Map
Chromosome 19
52.00 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:56826209-56870012 bp, + strand
From VEGA annotation of GRCm38

  43804 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12850  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tdrd1

Human
homologs
Human Homolog TDRD1, tudor domain containing 1
NCBI Gene ID 56165
neXtProt AC  NX_Q9BXT4
Human Synonyms  CT41.1
Human Chr (Location)  10q25.3; chr10:114179256-114232666 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Male homozygous mice are sterile, displaying postnatal spermatogenic defects. Females are fertile.
 
Interactions
Tdrd1 interacts with 214 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cell differentiation, DNA methylation involved in gamete generation, ...
Component chromatoid body, cytoplasm, ...
Function metal ion binding, protein binding
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (39)    Tissues (22)    Images (16)
Theiler Stages: 9, 19, 21, 23, 26, 28
Assay TypeResults
Immunohistochemistry 14
RNA in situ 5
Northern blot 9
Western blot 3
RT-PCR 8
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000028359 (Evidence)
Ensembl Gene ModelENSMUSG00000025081 (Evidence)
Entrez Gene83561 (Evidence)
UniGene247541
DFCITC1585319
DoTSDT.101151320, DT.103549614, DT.110862677, DT.40136930
PDB4B9W, 4B9X
Consensus CDS ProjectCCDS29922.1
International Mouse Knockout Project StatusTdrd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028359 VEGA Gene Model | MGI Sequence Detail 43804 C57BL/6J ±  kb
transcript OTTMUST00000070293 VEGA | MGI Sequence Detail 5047 Not Applicable 
polypeptide OTTMUSP00000035795 VEGA | MGI Sequence Detail 1172 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(22) UniProt(1)
Polymorphisms SNPs within 2kb(490 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002999 Tudor domain
InterPro IPR002893 Zinc finger, MYND-type
Protein Ontology PR:000016216 tudor domain-containing protein 1
References (Earliest) J:68614 Wang PJ, et al., An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr;27(4):422-6
(Latest) J:197673 Saxe JP, et al., Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J. 2013 Jul 3;32(13):1869-85
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory