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Tm6sf1 Gene Detail
Summary
  • Symbol
    Tm6sf1
  • Name
    transmembrane 6 superfamily member 1
  • Synonyms
    C630016D09Rik, MGC:25583
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933209
    NCBI Gene: 107769
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:81859001-81884079 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 45.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    147 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933209
protein coding gene Chr7:81859001-81884434 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032439
protein coding gene Chr7:83952883-83977882 (+)
A/J MGP_AJ_G0032417
protein coding gene Chr7:81955204-81980176 (+)
AKR/J MGP_AKRJ_G0032353
protein coding gene Chr7:83783044-83808048 (+)
BALB/cJ MGP_BALBcJ_G0032429
protein coding gene Chr7:81620198-81646068 (+)
C3H/HeJ MGP_C3HHeJ_G0032143
protein coding gene Chr7:84388972-84414795 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032920
protein coding gene Chr7:87226432-87251864 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029930
protein coding gene Chr7:84421253-84446639 (+)
CAST/EiJ MGP_CASTEiJ_G0031470
protein coding gene Chr7:75329515-75355447 (+)
CBA/J MGP_CBAJ_G0032108
protein coding gene Chr7:90143111-90169863 (+)
DBA/2J MGP_DBA2J_G0032263
protein coding gene Chr7:80484614-80509618 (+)
FVB/NJ MGP_FVBNJ_G0032217
protein coding gene Chr7:80421889-80446889 (+)
LP/J MGP_LPJ_G0032344
protein coding gene Chr7:85175587-85201685 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032254
protein coding gene Chr7:90198899-90223903 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032940
protein coding gene Chr7:83193251-83218691 (+)
PWK/PhJ MGP_PWKPhJ_G0031190
protein coding gene Chr7:73703540-73729632 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031032
protein coding gene Chr7:70188755-70215084 (+)
WSB/EiJ MGP_WSBEiJ_G0031587
protein coding gene Chr7:83556445-83582110 (+)



Homology
more
  • Human Ortholog
    TM6SF1, transmembrane 6 superfamily member 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TM6SF1, transmembrane 6 superfamily member 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 53346
    neXtProt AC: NX_Q9BZW5
    UniProt: Q9BZW5

  • Chr Location
    15q25.2; chr15:83107572-83145403 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 107769 NCBI Gene Model | MGI Sequence Detail 25079 C57BL/6J ±  kb
transcript NM_145375 RefSeq | MGI Sequence Detail 2234 C57BL/6  
polypeptide P58749 UniProt | EBI | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141947, MGI:2384810, MGI:2441917
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:219217 Tam WY, et al., Transmembrane 6 superfamily 1 (Tm6sf1) is a novel lysosomal transmembrane protein. Protoplasma. 2015 Jul;252(4):977-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory