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Setbp1
Gene Detail
Symbol

Name
ID
Setbp1
SET binding protein 1
MGI:1933199
Synonyms
mKIAA0437, Seb
Feature Type
protein coding gene
Genetic Map
Chromosome 18
52.67 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr18:78750380-79109391 bp, - strand
From VEGA annotation of GRCm38

  359012 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9192  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Setbp1

Human
homologs
Human Homolog SETBP1, SET binding protein 1
NCBI Gene ID 26040
neXtProt AC  NX_Q9Y6X0
Human Synonyms  MRD29, SEB
Human Chr (Location)  18q21.1; chr18:44680173-45068510 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human SETBP1
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Setbp1 interacts with 462 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process biological_process
Component nucleus
Function DNA binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (54)    Tissues (45)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 54
cDNA source data(41)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(43) cDNA(41) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000017269 (Evidence)
Ensembl Gene ModelENSMUSG00000024548 (Evidence)
Entrez Gene240427 (Evidence)
UniGene312871
DFCITC1708766, TC1583150, TC1657714
DoTSDT.97342707, DT.94142273, DT.101725336, DT.527096
NIA Mouse Gene IndexU038589
Consensus CDS ProjectCCDS29362.2
International Mouse Knockout Project StatusSetbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017269 VEGA Gene Model | MGI Sequence Detail 359012 C57BL/6J ±  kb
transcript OTTMUST00000041809 VEGA | MGI Sequence Detail 9953 Not Applicable 
polypeptide OTTMUSP00000018796 VEGA | MGI Sequence Detail 1535 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(3281 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017956 AT hook, DNA-binding motif
Protein Ontology PR:000014718 SET-binding protein
References
(Earliest) J:67956 Minakuchi M, et al., Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET. Eur J Biochem. 2001 Mar;268(5):1340-51
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory