Setbp1
Gene Detail

Symbol Name ID

Setbp1 SET binding protein 1 MGI:1933199

Synonyms

mKIAA0437, Seb

Feature Type

protein coding gene

Genetic Map

Chromosome 18

52.67 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr18:78750380-79109391 bp, - strand From VEGA annotation of GRCm38   359012 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9192  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Setbp1

Human homologs

Human Homolog		SETBP1, SET binding protein 1
NCBI Gene ID		26040
neXtProt AC		NX_Q9Y6X0
Human Synonyms		SEB
Human Chr (Location)		18q21.1; chr18:42260138-42648475 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SETBP1

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	biological_process
Component	nucleus
Function	DNA binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (53)    Tissues (44)    Images (10)
Theiler Stages: 19, 23, 28

Assay Type	Results
RNA in situ	53

cDNA source data(41)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(42) cDNA(41) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000017269 (Evidence)
Ensembl Gene Model	ENSMUSG00000024548 (Evidence)
Entrez Gene	240427 (Evidence)
UniGene	312871
DFCI	TC1583150, TC1657714, TC1708766
DoTS	DT.101725336, DT.527096, DT.94142273, DT.97342707
NIA Mouse Gene Index	U038589
Consensus CDS Project	CCDS29362.2
International Mouse Knockout Project Status	Setbp1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017269	VEGA Gene Model | MGI Sequence Detail	359012	C57BL/6J
transcript	OTTMUST00000041809	VEGA | MGI Sequence Detail	9953	Not Applicable
polypeptide	OTTMUSP00000018796	VEGA | MGI Sequence Detail	1535	Not Applicable

All sequences(31) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(2284 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017956	AT hook, DNA-binding motif
Protein Ontology	PR:000014718	SET-binding protein

References

(Earliest) J:67956 Minakuchi M, et al., Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET. Eur J Biochem. 2001 Mar;268(5):1340-51
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)