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Ctps2 Gene Detail
Summary
  • Symbol
    Ctps2
  • Name
    cytidine 5'-triphosphate synthase 2
  • Synonyms
    A830031M15Rik, CTPsH
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933185
    NCBI Gene: 55936
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:161684234-161815504 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 75.09 cM, cytoband F5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3136 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933185
 protein coding gene ChrX:161684234-161817537 (+)
129S1/SvImJ ENSMUSG00200026471
 protein coding gene ChrX:138411635-138542916 (+)
A/J ENSMUSG00195035647
 protein coding gene ChrX:143531947-143663257 (+)
AKR/J ENSMUSG00220029429
 protein coding gene ChrX:135387135-135516461 (+)
BALB/cJ ENSMUSG00180038819
 protein coding gene ChrX:138903449-139032759 (+)
C3H/HeJ ENSMUSG00175025201
 protein coding gene ChrX:143467657-143598944 (+)
C57BL/6NJ ENSMUSG00215014368
 protein coding gene ChrX:139302044-139433327 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033550
 protein coding gene ChrX:151222021-151353844 (+)
CAST/EiJ ENSTCUG00005030372
 protein coding gene ChrX:141035407-141163292 (+)
CBA/J ENSMUSG00210037473
 protein coding gene ChrX:140809908-140941201 (+)
DBA/2J ENSMUSG00185029572
 protein coding gene ChrX:155738536-155869822 (+)
FVB/NJ ENSMUSG00205026708
 protein coding gene ChrX:139395615-139526920 (+)
JF1/MsJ ENSUMUG00000020401
 protein coding gene ChrX:176133323-176260107 (+)
LP/J ENSMUSG00230024539
 protein coding gene ChrX:162527867-162659147 (+)
NOD/ShiLtJ ENSMUSG00190032606
 protein coding gene ChrX:139914738-140046010 (+)
NZO/HlLtJ ENSMUSG00225037884
 protein coding gene ChrX:165917146-166048415 (+)
PWK/PhJ ENSLUMG00010038483
 protein coding gene ChrX:137206741-137333430 (+)
SPRET/EiJ ENSMSPG00010018501
 protein coding gene ChrX:142338902-142461665 (+)
WSB/EiJ ENSIUOG00005024376
 protein coding gene ChrX:140218273-140342847 (+)



Homology
more
  • Human Ortholog
    CTPS2, CTP synthase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CTPS2, CTP synthase 2
  • Synonyms
    GATD5B
  • Links
    NCBI Gene ID: 56474
    UniProt: Q9NRF8

  • Chr Location
    Xp22.2; chrX:16587950-16712976 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    4 images
    18 phenotype references
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    123
  • cDNA Data
    99
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031360 Ensembl Gene Model | MGI Sequence Detail 131271 C57BL/6J ±  kb
transcript ENSMUST00000112301 Ensembl | MGI Sequence Detail 3099 Not Applicable  
polypeptide ENSMUSP00000107920 Ensembl | MGI Sequence Detail 586 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 99
    cDNA 99

    Microarray probesets 8
Other
Accession IDs
less
MGI:2147879
References
more
  • Summaries
    All 56
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 18
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:348981 Soudais C, et al., Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice. Nat Commun. 2024 Mar 4;15(1):1982
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory