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Nop58 Gene Detail
Summary
  • Symbol
    Nop58
  • Name
    NOP58 ribonucleoprotein
  • Synonyms
    MSSP, Nol5, SIK similar protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933184
    NCBI Gene: 55989
  • Gene Overview
    MyGene.info: NOP58
Location & Maps
more
  • Sequence Map
    Chr1:59684971-59719044 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34074 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 30.38 cM, cytoband C2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NOP58, NOP58 ribonucleoprotein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NOP58, NOP58 ribonucleoprotein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC120, NOP5, NOP5/NOP58
  • Links
    NCBI Gene ID: 51602
    neXtProt AC: NX_Q9Y2X3

  • Chr Location
    2q33.1; chr2:202265792-202303661 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7024
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: NOP58
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    224
  • Chemically induced (other)
    1
  • Gene trapped
    222
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Nop58
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047257 VEGA Gene Model | MGI Sequence Detail 34074 C57BL/6J ±  kb
transcript OTTMUST00000122181 VEGA | MGI Sequence Detail 9507 Not Applicable  
polypeptide OTTMUSP00000067100 VEGA | MGI Sequence Detail 536 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    187 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 129
    cDNA 128
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:62560 Yang Y, et al., Conserved composition of mammalian box H/ACA and box C/D small nucleolar ribonucleoprotein particles and their interaction with the common factor Nopp140. Mol Biol Cell. 2000 Feb;11(2):567-77
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory