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Eif3d Gene Detail
Summary
  • Symbol
    Eif3d
  • Name
    eukaryotic translation initiation factor 3, subunit D
  • Synonyms
    66/67kDa, eIF3p66, Eif3s7, mouse translation initiation factor eIF3 p66
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933181
    NCBI Gene: 55944
  • Gene Overview
    MyGene.info: EIF3D
Location & Maps
more
  • Sequence Map
    Chr15:77958998-77970824 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11827 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.92 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EIF3D, eukaryotic translation initiation factor 3 subunit D
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EIF3D, eukaryotic translation initiation factor 3 subunit D
    Orthology source: HomoloGene, HGNC
  • Synonyms
    eIF3-p66, EIF3S7, eIF3-zeta
  • Links
    NCBI Gene ID: 8664
    neXtProt AC: NX_O15371

  • Chr Location
    22q13.1; chr22:36510850-36529431 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    40
  • Chemically induced (other)
    2
  • Gene trapped
    33
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    4 involving Eif3d
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016554 Ensembl Gene Model | MGI Sequence Detail 11827 C57BL/6J ±  kb
transcript ENSMUST00000100484 Ensembl | MGI Sequence Detail 1910 Not Applicable  
polypeptide ENSMUSP00000098053 Ensembl | MGI Sequence Detail 548 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    125 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000006976 eukaryotic translation initiation factor 3 subunit D
  • InterPro Domains
    IPR007783 Eukaryotic translation initiation factor 3 subunit D
Molecular
Reagents
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  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:2145893
References
more
  • Summaries
    All 30
    Diseases 1
    Gene Ontology 5
    Phenotypes 27
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:204915 Zeng L, et al., The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control. J Biol Chem. 2013 Oct 18;288(42):30087-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory