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Rnf114 Gene Detail
Summary
  • Symbol
    Rnf114
  • Name
    ring finger protein 114
  • Synonyms
    1110008J21Rik, Zfp313, Znf228
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933159
    NCBI Gene: 81018
Location & Maps
more
  • Sequence Map
    Chr2:167492645-167516173 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23529 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 87.25 cM, cytoband H3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    RNF114, ring finger protein 114
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RNF114, ring finger protein 114
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PSORS12, ZNF313
  • Links
    NCBI Gene ID: 55905
    neXtProt AC: NX_Q9Y508

  • Chr Location
    20q13.13; chr20:49936377-49953885 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    10
  • Gene trapped
    9
  • Targeted
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001140 VEGA Gene Model | MGI Sequence Detail 23529 C57BL/6J ±  kb
transcript OTTMUST00000038920 VEGA | MGI Sequence Detail 3001 Not Applicable  
polypeptide OTTMUSP00000017392 VEGA | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    149 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000014071 E3 ubiquitin-protein ligase RNF114
  • EC
  • InterPro Domains
    IPR008598 Drought induced 19 protein type, zinc-binding domain
    IPR027370 RING-type zinc-finger, LisH dimerisation motif
    IPR015880 Zinc finger, C2H2-like
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001841 Zinc finger, RING-type
    IPR017907 Zinc finger, RING-type, conserved site
Molecular
Reagents
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  • All nucleic 255
    cDNA 253
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
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MGI:1920985, MGI:2138866, MGI:2139384
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228628 Han J, et al., ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.). Cell Death Differ. 2013 Aug;20(8):1055-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory