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Acox3
Gene Detail
 Symbol
Name
ID
Acox3
acyl-Coenzyme A oxidase 3, pristanoyl
MGI:1933156
Synonyms EST-s59, PCOX, pristanoyl-CoA oxidase
Feature Type protein coding gene
Genetic Map
Chromosome 5
18.32 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:35583040-35613801 bp, + strand
From VEGA annotation of GRCm38

  30762 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37792  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: acyl-CoA oxidase
Gene Tree: Acox3

Human
homologs
Human Homolog ACOX3, acyl-CoA oxidase 3, pristanoyl
NCBI Gene ID 8310
neXtProt AC  NX_O15254
Human Chr (Location)  4p15.3; chr4:8366282-8440725 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(2) Radiation induced(4)
Genomic Mutations involving Acox3 (5)
Incidental mutations (data from APF )
Alleles Annotated to Human Diseases(4)   
Interactions
Acox3 interacts with 214 markers (Mir1b, Mir10a, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, ...
Component membrane, mitochondrion, ...
Function acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (131)    Tissues (126)    Images (5)
Theiler Stages: 17, 20, 22, 26, 28
Assay TypeResults
RNA in situ 114
Northern blot 17
cDNA source data(31)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(34) cDNA(32) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000023571 (Evidence)
Ensembl Gene ModelENSMUSG00000029098 (Evidence)
Entrez Gene80911 (Evidence)
UniGene291503
DFCITC1581230, TC1584803, TC1605439, TC1607114
NIA Mouse Gene IndexU005503
EC1.3.3.6
Consensus CDS ProjectCCDS19232.1
International Mouse Knockout Project StatusAcox3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023571 VEGA Gene Model | MGI Sequence Detail 30762 C57BL/6J ±  kb
transcript OTTMUST00000057521 VEGA | MGI Sequence Detail 2642 Not Applicable 
polypeptide OTTMUSP00000027750 VEGA | MGI Sequence Detail 728 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(14) UniProt(5)
Polymorphisms SNPs within 2kb(164 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009100 Acyl-CoA dehydrogenase/oxidase
InterPro IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
InterPro IPR012258 Acyl-CoA oxidase
InterPro IPR002655 Acyl-CoA oxidase, C-terminal
InterPro IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Protein Ontology PR:000003644 peroxisomal acyl-coenzyme A oxidase 3
References (Earliest) J:72462 Knoll A, et al., Peroxisomal beta-oxidation enzyme gene expression in the developing mouse brain. Neurosci Lett. 2000 May 19;285(3):201-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(38)
Other
accession IDs
MGI:2183033

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory