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Acox3
Gene Detail
Symbol

Name
ID
Acox3
acyl-Coenzyme A oxidase 3, pristanoyl
MGI:1933156
Synonyms
EST-s59, PCOX, pristanoyl-CoA oxidase
Feature Type
protein coding gene
Genetic Map
Chromosome 5
18.32 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:35583040-35615352 bp, + strand
From VEGA annotation of GRCm38

  32313 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37792  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ACOX3
Protein SuperFamily: acyl-CoA oxidase
Gene Tree: Acox3

Human
homologs
ACOX3, acyl-CoA oxidase 3, pristanoyl
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 8310
neXtProt AC: NX_O15254

Human Chr (Location): 4p15.3; chr4:8366263-8440725 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Chemically induced (ENU)(1) Gene trapped(2) Radiation induced(5)
Genomic Mutations involving Acox3 (6)
Incidental mutations (data from APF )
Mutations Annotated to Human Diseases (4)    Phenotype Images(4)
Interactions
Acox3 interacts with 214 markers (Mir1b, Mir10a, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, ...
Component membrane, mitochondrion, ...
Function acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (131)    Tissues (126)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 114
Northern blot 17
cDNA source data(31)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase acox3 ; ZFIN acox3    NEW 
Molecular
reagents
All nucleic(34) cDNA(32) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000023571 (Evidence)
Ensembl Gene Model ENSMUSG00000029098 (Evidence)
Entrez Gene 80911 (Evidence)
UniGene 291503
DFCI TC1581230, TC1584803, TC1605439, TC1607114
NIA Mouse Gene Index U005503
EC 1.3.3.6
Consensus CDS Project CCDS19232.1
International Mouse Phenotyping Consortium Status Acox3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023571 VEGA Gene Model | MGI Sequence Detail 32313 C57BL/6J ±  kb
transcript OTTMUST00000057518 VEGA | MGI Sequence Detail 3976 Not Applicable 
polypeptide OTTMUSP00000027748 VEGA | MGI Sequence Detail 700 Not Applicable 

For the selected sequences
All sequences(77) RefSeq(16) UniProt(5)
Polymorphisms
SNPs within 2kb(170 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
InterPro IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
InterPro IPR012258 Acyl-CoA oxidase
InterPro IPR002655 Acyl-CoA oxidase, C-terminal
InterPro IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Protein Ontology PR:000003644 peroxisomal acyl-coenzyme A oxidase 3
References
(Earliest) J:72462 Knoll A, et al., Peroxisomal beta-oxidation enzyme gene expression in the developing mouse brain. Neurosci Lett. 2000 May 19;285(3):201-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGI:2183033

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory