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Mettl27 Gene Detail
Summary
  • Symbol
    Mettl27
  • Name
    methyltransferase like 27
  • Synonyms
    MGC:8159, Wbscr27
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933146
    NCBI Gene: 79565
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:134932368-134942637 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 74.89 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933146
protein coding gene Chr5:134932328-134942637 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030166
protein coding gene Chr5:139401076-139411644 (+)
A/J MGP_AJ_G0030134
protein coding gene Chr5:133455070-133464908 (+)
AKR/J MGP_AKRJ_G0030067
protein coding gene Chr5:137796071-137805856 (+)
BALB/cJ MGP_BALBcJ_G0030144
protein coding gene Chr5:134810477-134820812 (+)
C3H/HeJ MGP_C3HHeJ_G0029860
protein coding gene Chr5:138352075-138363318 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030597
protein coding gene Chr5:144635539-144645766 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0029269
protein coding gene Chr5:137777524-137787234 (+)
CBA/J MGP_CBAJ_G0029830
protein coding gene Chr5:150285534-150295916 (+)
DBA/2J MGP_DBA2J_G0029981
protein coding gene Chr5:133351550-133361554 (+)
FVB/NJ MGP_FVBNJ_G0029936
protein coding gene Chr5:132483725-132494001 (+)
LP/J MGP_LPJ_G0030069
protein coding gene Chr5:139860350-139871914 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029968
protein coding gene Chr5:153307713-153318100 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030637
protein coding gene Chr5:137529220-137540844 (+)
PWK/PhJ MGP_PWKPhJ_G0028984
protein coding gene Chr5:132395292-132405357 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028819
protein coding gene Chr5:135099977-135111000 (+)
WSB/EiJ MGP_WSBEiJ_G0029343
protein coding gene Chr5:138284966-138295746 (+)



Homology
more
  • Human Ortholog
    METTL27, methyltransferase like 27
  • Vertebrate Orthologs
    9
  • Human Ortholog
    METTL27, methyltransferase like 27
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WBSCR27
  • Links
    NCBI Gene ID: 155368
    neXtProt AC: NX_Q8N6F8
    UniProt: Q8N6F8

  • Chr Location
    7q11.23; chr7:73834590-73842527 (-)  GRCh38.p7

Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040557 Ensembl Gene Model | MGI Sequence Detail 10270 C57BL/6J ±  kb
transcript ENSMUST00000111218 Ensembl | MGI Sequence Detail 1387 Not Applicable  
polypeptide ENSMUSP00000106849 Ensembl | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 7
    Genomic 1
    cDNA 6

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141200
References
more
  • Summaries
    All 27
    Diseases 2
    Phenotypes 7
  • Earliest
    J:73830 DeSilva U, et al., Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome. Genome Res. 2002 Jan;12(1):3-15
  • Latest
    J:216195 Segura-Puimedon M, et al., Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder. Hum Mol Genet. 2014 Dec 15;23(24):6481-94

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory