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Pgam2
Gene Detail
Symbol

Name
ID
Pgam2
phosphoglycerate mutase 2
MGI:1933118
Feature Type
protein coding gene
Genetic Map
Chromosome 11
3.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:5801640-5803733 bp, - strand
From VEGA annotation of GRCm38

  2094 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56228  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: cofactor-dependent phosphoglycerate mutase
Gene Tree: Pgam2

Human
homologs
Human Homolog PGAM2, phosphoglycerate mutase 2 (muscle)
NCBI Gene ID 5224
neXtProt AC  NX_P15259
Human Synonyms  GSD10, PGAMM, PGAM-M
Human Chr (Location)  7p13-p12; chr7:44062727-44065587 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PGAM2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from APF )
Interactions
Pgam2 interacts with 24 markers (Mir137, Mir293, Mir325, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (381)    Tissues (119)    Images (57)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 379
RT-PCR 2
cDNA source data(5)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(5) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000005095 (Evidence)
Ensembl Gene ModelENSMUSG00000020475 (Evidence)
Entrez Gene56012 (Evidence)
DFCITC1679293, TC1578210
DoTSDT.535537, DT.94404635, DT.55283488
NIA Mouse Gene IndexU032474
EC5.4.2.11, 5.4.2.4, 3.1.3.13
Consensus CDS ProjectCCDS24404.1
International Mouse Knockout Project StatusPgam2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005095 VEGA Gene Model | MGI Sequence Detail 2094 C57BL/6J ±  kb
transcript OTTMUST00000011391 VEGA | MGI Sequence Detail 840 Not Applicable 
polypeptide OTTMUSP00000005308 VEGA | MGI Sequence Detail 253 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013078 Histidine phosphatase superfamily, clade-1
InterPro IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site
InterPro IPR005952 Phosphoglycerate mutase 1
Protein Ontology PR:000012593 phosphoglycerate mutase 2
References
(Earliest) J:203034 Fundele R, et al., Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse. Dev Biol. 1987 Dec;124(2):562-6
(Latest) J:212982 Mikawa T, et al., Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2. J Cell Biol. 2014 Mar 3;204(5):729-45
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory