About   Help   FAQ
Pgam2
Gene Detail
Symbol

Name
ID
Pgam2
phosphoglycerate mutase 2
MGI:1933118
Feature Type
protein coding gene
Genetic Map
Chromosome 11
3.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:5801640-5803733 bp, - strand
From VEGA annotation of GRCm38

  2094 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56228  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PGAM2
Protein SuperFamily: cofactor-dependent phosphoglycerate mutase
Gene Tree: Pgam2

Human
homologs
PGAM2, phosphoglycerate mutase 2 (muscle)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5224
neXtProt AC: NX_P15259

Human Synonyms: GSD10, PGAMM, PGAM-M

Human Chr (Location): 7p13-p12; chr7:44062727-44065972 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PGAM2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from APF , CvDC )
Interactions
Pgam2 interacts with 24 markers (Mir137, Mir293, Mir325, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (381)    Tissues (119)    Images (57)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 379
RT-PCR 2
cDNA source data(5)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase pgam2    NEW 
Molecular
reagents
All nucleic(8) cDNA(5) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000005095 (Evidence)
Ensembl Gene Model ENSMUSG00000020475 (Evidence)
Entrez Gene 56012 (Evidence)
DFCI TC1679293, TC1578210
DoTS DT.94404635, DT.55283488, DT.535537
NIA Mouse Gene Index U032474
EC 5.4.2.11, 3.1.3.13, 5.4.2.4
Consensus CDS Project CCDS24404.1
International Mouse Phenotyping Consortium Status Pgam2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005095 VEGA Gene Model | MGI Sequence Detail 2094 C57BL/6J ±  kb
transcript OTTMUST00000011391 VEGA | MGI Sequence Detail 840 Not Applicable 
polypeptide OTTMUSP00000005308 VEGA | MGI Sequence Detail 253 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013078 Histidine phosphatase superfamily, clade-1
InterPro IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site
InterPro IPR005952 Phosphoglycerate mutase 1
Protein Ontology PR:000012593 phosphoglycerate mutase 2
References
(Earliest) J:203034 Fundele R, et al., Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse. Dev Biol. 1987 Dec;124(2):562-6
(Latest) J:212982 Mikawa T, et al., Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2. J Cell Biol. 2014 Mar 3;204(5):729-45
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/28/2015
MGI 5.22
The Jackson Laboratory