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Parp9 Gene Detail
Summary
  • Symbol
    Parp9
  • Name
    poly (ADP-ribose) polymerase family, member 9
  • Synonyms
    MGC:7868
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933117
    NCBI Gene: 80285
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:35758840-35792975 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    199 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933117
protein coding gene Chr16:35758840-35792991 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022774
protein coding gene Chr16:34291705-34330077 (+)
A/J MGP_AJ_G0022739
protein coding gene Chr16:32629257-32663270 (+)
AKR/J MGP_AKRJ_G0022712
protein coding gene Chr16:33772173-33808025 (+)
BALB/cJ MGP_BALBcJ_G0022741
protein coding gene Chr16:32751791-32785033 (+)
C3H/HeJ MGP_C3HHeJ_G0022506
protein coding gene Chr16:33899647-33935447 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023190
protein coding gene Chr16:35027353-35074295 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020708
protein coding gene Chr16:32984145-33020014 (+)
CAST/EiJ MGP_CASTEiJ_G0022034
protein coding gene Chr16:34127328-34162262 (+)
CBA/J MGP_CBAJ_G0022476
protein coding gene Chr16:36450265-36492409 (+)
DBA/2J MGP_DBA2J_G0022609
protein coding gene Chr16:32452779-32487812 (+)
FVB/NJ MGP_FVBNJ_G0022584
protein coding gene Chr16:32449596-32482767 (+)
LP/J MGP_LPJ_G0022676
protein coding gene Chr16:34021777-34059484 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022603
protein coding gene Chr16:35722544-35759518 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023202
protein coding gene Chr16:33827840-33866921 (+)
PWK/PhJ MGP_PWKPhJ_G0021775
protein coding gene Chr16:32864232-32905249 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021606
protein coding gene Chr16:33646750-33682779 (+)
WSB/EiJ MGP_WSBEiJ_G0022078
protein coding gene Chr16:33755973-33794920 (+)



Homology
more
  • Human Ortholog
    PARP9, poly(ADP-ribose) polymerase family member 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARP9, poly(ADP-ribose) polymerase family member 9
  • Synonyms
    ARTD9, BAL, BAL1, MGC:7868
  • Links
    NCBI Gene ID: 83666
    neXtProt AC: NX_Q8IXQ6
    UniProt: Q8IXQ6

  • Chr Location
    3q21.1; chr3:122527910-122564676 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit higher viral titers in the liver, lungs, spleen, and brains, and decreased type I IFN production in response to infection with RNA virus.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022906 Ensembl Gene Model | MGI Sequence Detail 34136 C57BL/6J ±  kb
transcript ENSMUST00000114878 Ensembl | MGI Sequence Detail 3548 Not Applicable  
polypeptide ENSMUSP00000110528 Ensembl | MGI Sequence Detail 830 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146631
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:306337 Xing J, et al., Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells. Nat Commun. 2021 May 11;12(1):2681

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory