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Bcl9l Gene Detail
Summary
  • Symbol
    Bcl9l
  • Name
    B cell CLL/lymphoma 9-like
  • Synonyms
    DLNB11, MGC:7014
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933114
    NCBI Gene: 80288
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:44482825-44511896 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 24.84 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933114
protein coding gene Chr9:44482366-44511901 (.)
129S1/SvImJ MGP_129S1SvImJ_G0034712
protein coding gene Chr9:42978695-43007598 (+)
A/J MGP_AJ_G0034693
protein coding gene Chr9:41775288-41804148 (+)
AKR/J MGP_AKRJ_G0034620
protein coding gene Chr9:42660795-42672047 (+)
BALB/cJ MGP_BALBcJ_G0034684
protein coding gene Chr9:41537752-41550289 (+)
C3H/HeJ MGP_C3HHeJ_G0034395
protein coding gene Chr9:43099432-43128078 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035205
protein coding gene Chr9:44248644-44279419 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032120
protein coding gene Chr9:41375682-41386888 (+)
CAST/EiJ MGP_CASTEiJ_G0033717
protein coding gene Chr9:42942955-42973308 (+)
CBA/J MGP_CBAJ_G0034367
protein coding gene Chr9:45867889-45898940 (+)
DBA/2J MGP_DBA2J_G0034526
protein coding gene Chr9:41694152-41705466 (+)
FVB/NJ MGP_FVBNJ_G0034467
protein coding gene Chr9:40937002-40964757 (+)
LP/J MGP_LPJ_G0034607
protein coding gene Chr9:43279139-43305879 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034511
protein coding gene Chr9:47697184-47726913 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035226
protein coding gene Chr9:42544239-42575277 (+)
PWK/PhJ MGP_PWKPhJ_G0033423
protein coding gene Chr9:41575678-41586949 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033257
protein coding gene Chr9:42862688-42891776 (+)
WSB/EiJ MGP_WSBEiJ_G0033830
protein coding gene Chr9:42580689-42610112 (+)



Homology
more
  • Human Ortholog
    BCL9L, BCL9 like
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BCL9L, BCL9 like
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B9L, BCL9-2, DLNB11
  • Links
    NCBI Gene ID: 283149
    neXtProt AC: NX_Q86UU0
    UniProt: Q86UU0

  • Chr Location
    11q23.3; chr11:118896140-118926072 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    10 phenotype references
Mice carrying homozygous floxed Bcl9 and Bcl9l alleles, inactivated in muscle cells, exhibit impaired muscle regeneration due to increased apoptosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063382 Ensembl Gene Model | MGI Sequence Detail 29072 C57BL/6J ±  kb
transcript ENSMUST00000218183 Ensembl | MGI Sequence Detail 6771 Not Applicable  
polypeptide ENSMUSP00000151837 Ensembl | MGI Sequence Detail 1494 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 51
    Primer pair 1
    Other 1

    Microarray probesets 6
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:245023 Cantu C, et al., A cytoplasmic role of Wnt/beta-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation. Sci Signal. 2017 Feb 07;10(465)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory