About   Help   FAQ
Gpr146 Gene Detail
Summary
  • Symbol
    Gpr146
  • Name
    G protein-coupled receptor 146
  • Synonyms
    MGC:7035, PGR8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933113
    NCBI Gene: 80290
  • Gene Overview
    MyGene.info: GPR146
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:139377697-139396415 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 78.49 cM, cytoband G1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933113
protein coding gene Chr5:139376431-139396415 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030283
protein coding gene Chr5:144352291-144374366 (+)
A/J MGP_AJ_G0030252
protein coding gene Chr5:138235524-138255342 (+)
AKR/J MGP_AKRJ_G0030184
protein coding gene Chr5:142542112-142560630 (+)
BALB/cJ MGP_BALBcJ_G0030269
protein coding gene Chr5:139482026-139500496 (+)
C3H/HeJ MGP_C3HHeJ_G0029980
protein coding gene Chr5:143319243-143338884 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030714
protein coding gene Chr5:149673864-149692310 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027932
protein coding gene Chr5:132098447-132117013 (+)
CAST/EiJ MGP_CASTEiJ_G0029385
protein coding gene Chr5:142733608-142753568 (+)
CBA/J MGP_CBAJ_G0029950
protein coding gene Chr5:155841467-155867298 (+)
DBA/2J MGP_DBA2J_G0030100
protein coding gene Chr5:138045595-138063961 (+)
FVB/NJ MGP_FVBNJ_G0030055
protein coding gene Chr5:137151628-137175024 (+)
LP/J MGP_LPJ_G0030186
protein coding gene Chr5:144964240-144984193 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030086
protein coding gene Chr5:158515517-158535345 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030754
protein coding gene Chr5:142354183-142377318 (+)
PWK/PhJ MGP_PWKPhJ_G0029100
protein coding gene Chr5:137048952-137068883 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028936
protein coding gene Chr5:140046334-140065199 (+)
WSB/EiJ MGP_WSBEiJ_G0029459
protein coding gene Chr5:143121899-143142121 (+)



Homology
more
  • Human Ortholog
    GPR146, G protein-coupled receptor 146
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GPR146, G protein-coupled receptor 146
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PGR8
  • Links
    NCBI Gene ID: 115330
    neXtProt AC: NX_Q96CH1
    UniProt: Q96CH1

  • Chr Location
    7p22.3; chr7:1044573-1059269 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044197 Ensembl Gene Model | MGI Sequence Detail 18719 C57BL/6J ±  kb
transcript ENSMUST00000100514 Ensembl | MGI Sequence Detail 4264 Not Applicable  
polypeptide ENSMUSP00000098083 Ensembl | MGI Sequence Detail 333 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 6
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:274675 Martin JH, et al., Investigation into the presence and functional significance of proinsulin C-peptide in the female germlinedagger. Biol Reprod. 2019 May 1;100(5):1275-1289

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory