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Cxcl16
Gene Detail
 Symbol
Name
ID
Cxcl16
chemokine (C-X-C motif) ligand 16
MGI:1932682
Synonyms 0910001K24Rik, Scavenger Receptor, SR-PSOX, SR-PSOX/CXCL16
Feature Type protein coding gene
Genetic Map
Chromosome 11
42.99 cM, cytoband B4
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:70453983-70459984 bp, - strand
From VEGA annotation of GRCm38

  6002 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49694  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Cxcl16

Human
homologs
Human Homolog CXCL16, chemokine (C-X-C motif) ligand 16
NCBI Gene ID 58191
neXtProt AC  NX_Q9H2A7
Human Synonyms  CXCLG16, SRPSOX, SR-PSOX
Human Chr (Location)  17p13; chr17:4733529-4739928 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit decreased NK T cells, decreased secretion and serum levels of IL4 and IFN-gamma, and decreased inhibition of B16 melanoma cell growth by alpha-galactosylceramide treatment.
 
Phenotype Images(4)
Interactions
Cxcl16 interacts with 215 markers (Mir1b, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cell chemotaxis, chemotaxis, ...
Component extracellular space, integral component of membrane, ...
Function chemokine activity, cytokine activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (44)    Tissues (17)    Images (18)
Theiler Stages: 23
Assay TypeResults
RNA in situ 44
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000006042 (Evidence)
Ensembl Gene ModelENSMUSG00000018920 (Evidence)
Entrez Gene66102 (Evidence)
Consensus CDS ProjectCCDS24948.1
International Mouse Knockout Project StatusCxcl16
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006042 VEGA Gene Model | MGI Sequence Detail 6002 C57BL/6J ±  kb
transcript OTTMUST00000013602 VEGA | MGI Sequence Detail 2699 Not Applicable 
polypeptide OTTMUSP00000006308 VEGA | MGI Sequence Detail 246 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(60 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026296 CXC chemokine 16
Protein Ontology PR:000001804 C-X-C motif chemokine 16
References (Earliest) J:65117 Matloubian M, et al., A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat Immunol. 2000 Oct;1(4):298-304
(Latest) J:198188 Izquierdo MC, et al., TWEAK (tumor necrosis factor-like weak inducer of apoptosis) activates CXCL16 expression during renal tubulointerstitial inflammation. Kidney Int. 2012 Jun;81(11):1098-107
All references(42)
Other
accession IDs
MGI:1913352, MGI:2144468, MGI:2144594

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory