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Ndst4 Gene Detail
Summary
  • Symbol
    Ndst4
  • Name
    N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
  • Synonyms
    4930439H17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1932545
    NCBI Gene: 64580
Location & Maps
more
  • Sequence Map
    Chr3:125404076-125728899 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      324824 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 54.68 cM, cytoband H1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NDST4, N-deacetylase and N-sulfotransferase 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDST4, N-deacetylase and N-sulfotransferase 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NDST-4, N-HSST, NHSST4, N-HSST 4
  • Links
    NCBI Gene ID: 64579
    neXtProt AC: NX_Q9H3R1

  • Chr Location
    4q26; chr4:114827775-115113876 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Ndst4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025050 VEGA Gene Model | MGI Sequence Detail 324824 C57BL/6J ±  kb
transcript OTTMUST00000061638 VEGA | MGI Sequence Detail 7417 Not Applicable  
polypeptide OTTMUSP00000030274 VEGA | MGI Sequence Detail 872 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    4268 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1921219
References
more
  • Summaries
    All 32
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:178840 Dagalv A, et al., Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin. J Biol Chem. 2011 Dec 30;286(52):44433-40

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory