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Cyp4x1
Gene Detail
Symbol

Name
ID
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
MGI:1932403
Synonyms
Cyp4a28-ps
Feature Type
protein coding gene
Genetic Map
Chromosome 4
52.76 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:115106323-115134281 bp, - strand
From VEGA annotation of GRCm38

  27959 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75853  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: CYP4X1
Protein SuperFamily: cytochrome P450 CYP4B1
Gene Tree: Cyp4x1

Human
homologs
CYP4X1, cytochrome P450, family 4, subfamily X, polypeptide 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 260293
neXtProt AC: NX_Q8N118

Human Synonyms: CYPIVX1

Human Chr (Location): 1p33; chr1:46961364-47050751 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Cyp4x1 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Cyp4x1 interacts with 223 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, integral component of membrane, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (81)    Tissues (46)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 69
RT-PCR 12
cDNA source data(5)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(5) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000008620 (Evidence)
Ensembl Gene Model ENSMUSG00000047155 (Evidence)
Entrez Gene 81906 (Evidence)
UniGene 215544
NIA Mouse Gene Index U025394
EC 1.14.14.1
Consensus CDS Project CCDS18488.1
International Mouse Phenotyping Consortium Status Cyp4x1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008620 VEGA Gene Model | MGI Sequence Detail 27959 C57BL/6J ±  kb
transcript OTTMUST00000019519 VEGA | MGI Sequence Detail 4187 Not Applicable 
polypeptide OTTMUSP00000008957 VEGA | MGI Sequence Detail 481 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(175 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006145 cytochrome P450 4X1
References
(Earliest) J:68016 Gottgens B, et al., Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences. Genome Res. 2001 Jan;11(1):87-97
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:2449779

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory