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Rrbp1 Gene Detail
Summary
  • Symbol
    Rrbp1
  • Name
    ribosome binding protein 1
  • Synonyms
    1700087N07Rik, 5730465C04Rik, ES/130, mRRp0, mRRp10, mRRp15a, mRRp15b, mRRp16.8, mRRp1.8, mRRp2, mRRp41, mRRp47, mRRp5.4, p180
  • Feature Type
    protein coding gene
  • IDs
    MGI:1932395
    NCBI Gene: 81910
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:143789315-143853183 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 70.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2071 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1932395
 protein coding gene Chr2:143789315-143853216 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026579
 protein coding gene Chr2:147998331-148065046 (-)
A/J MGP_AJ_G0026543
 protein coding gene Chr2:142021696-142084662 (-)
AKR/J MGP_AKRJ_G0026517
 protein coding gene Chr2:146097739-146165810 (-)
BALB/cJ MGP_BALBcJ_G0026555
 protein coding gene Chr2:142469210-142532729 (-)
C3H/HeJ MGP_C3HHeJ_G0026298
 protein coding gene Chr2:146642810-146706340 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027000
 protein coding gene Chr2:152459842-152529774 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024377
 protein coding gene Chr2:136213440-136276667 (-)
CAST/EiJ MGP_CASTEiJ_G0025759
 protein coding gene Chr2:146948038-147033461 (-)
CBA/J MGP_CBAJ_G0026278
 protein coding gene Chr2:158007692-158073666 (-)
DBA/2J MGP_DBA2J_G0026412
 protein coding gene Chr2:141314269-141377488 (-)
FVB/NJ MGP_FVBNJ_G0026376
 protein coding gene Chr2:139901509-139964731 (-)
LP/J MGP_LPJ_G0026516
 protein coding gene Chr2:148172370-148238817 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026396
 protein coding gene Chr2:162233792-162301793 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027055
 protein coding gene Chr2:146101248-146166458 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025296
 protein coding gene Chr2:145125521-145207468 (-)
WSB/EiJ MGP_WSBEiJ_G0025832
 protein coding gene Chr2:147112031-147176104 (-)



Homology
more
  • Human Ortholog
    RRBP1, ribosome binding protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RRBP1, ribosome binding protein 1
  • Synonyms
    ES/130, ES130, hES, p180, RRp
  • Links
    NCBI Gene ID: 6238
    UniProt: Q9P2E9

  • Chr Location
    20p12.1; chr20:17613678-17682295 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    17
  • cDNA Data
    15
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027422 Ensembl Gene Model | MGI Sequence Detail 63869 C57BL/6J ±  kb
    transcript ENSMUST00000016072 Ensembl | MGI Sequence Detail 5177 Not Applicable  
    polypeptide ENSMUSP00000016072 Ensembl | MGI Sequence Detail 1464 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000014303 ribosome-binding protein 1
      (term hierarchy)
    • InterPro Domains
      IPR040248 Ribosome-binding protein 1
      IPR007794 Ribosome receptor lysine/proline rich
    • GlyGen
      Q99PL5 5 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 16
      Primer pair 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1920757, MGI:1926071
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 13
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:348395 Parlakgul G, et al., Spatial mapping of hepatic ER and mitochondria architecture reveals zonated remodeling in fasting and obesity. Nat Commun. 2024 May 10;15(1):3982
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/18/2025
    MGI 6.24     		The Jackson Laboratory