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Fkbpl
Gene Detail
 Symbol
Name
ID
Fkbpl
FK506 binding protein-like
MGI:1932127
Synonyms DIR1, NG7, Ppiase-X, WAF-1/CIP1 stabilizing protein 39, WISp39
Feature Type protein coding gene
Genetic Map
Chromosome 17
18.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:34644764-34646324 bp, + strand
From VEGA annotation of GRCm38

  1561 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10529  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Fkbpl

Human
homologs
Human Homolog FKBPL, FK506 binding protein like
NCBI Gene ID 63943
neXtProt AC  NX_Q9UIM3
Human Synonyms  DIR1, NG7, WISP39
Human Chr (Location)  6p21.3; chr6:32128707-32130290 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Fkbpl interacts with 2 markers (Mir383, Mir1902)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process chaperone-mediated protein folding, protein peptidyl-prolyl isomerization
Component endoplasmic reticulum membrane
Function FK506 binding, peptidyl-prolyl cis-trans isomerase activity
External Resources: FuncBase
Expression
cDNA source data(29)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) Genomic(1) cDNA(29)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000037080 (Evidence)
Ensembl Gene ModelENSMUSG00000033739 (Evidence)
Entrez Gene56299 (Evidence)
UniGene10025
DFCITC1581378
DoTSDT.99856240
NIA Mouse Gene IndexU145928
Consensus CDS ProjectCCDS28654.1
International Mouse Knockout Project StatusFkbpl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037080 VEGA Gene Model | MGI Sequence Detail 1561 C57BL/6J ±  kb
transcript OTTMUST00000095427 VEGA | MGI Sequence Detail 1270 Not Applicable 
polypeptide OTTMUSP00000053247 VEGA | MGI Sequence Detail 347 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(42) UniProt(2)
Polymorphisms SNPs within 2kb(21 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR019734 Tetratricopeptide repeat
InterPro IPR013026 Tetratricopeptide repeat-containing domain
InterPro IPR001440 Tetratricopeptide TPR-1
Protein Ontology PR:000007546 FK506-binding protein-like
References (Earliest) J:63109 Yung Yu C, et al., The human and mouse MHC class III region: a parade of 21 genes at the centromeric segment. Immunol Today. 2000 Jul;21(7):320-8
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory