About   Help   FAQ
Fkbpl Gene Detail
Summary
  • Symbol
    Fkbpl
  • Name
    FK506 binding protein-like
  • Synonyms
    DIR1, NG7, Ppiase-X, WAF-1/CIP1 stabilizing protein 39, WISp39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1932127
    NCBI Gene: 56299
Location & Maps
more
  • Sequence Map
    Chr17:34644764-34646324 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1561 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    FKBPL, FK506 binding protein like
  • Vertebrate Orthologs
    7
  • Human Ortholog
    FKBPL, FK506 binding protein like
    Orthology source: HomoloGene
  • Synonyms
    DIR1, FKBP4, NG7, WISP39
  • Links
    NCBI Gene ID: 63943
    neXtProt AC: NX_Q9UIM3

  • Chr Location
    6p21.3; chr6:32128707-32130308 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    11
  • Gene trapped
    9
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037080 VEGA Gene Model | MGI Sequence Detail 1561 C57BL/6J ±  kb
transcript OTTMUST00000095427 VEGA | MGI Sequence Detail 1270 Not Applicable  
polypeptide OTTMUSP00000053247 VEGA | MGI Sequence Detail 347 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    21 from dbSNP Build 137
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000007546 FK506-binding protein-like
  • InterPro Domains
    IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR001440 Tetratricopeptide repeat 1
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
less
  • All nucleic 30
    Genomic 1
    cDNA 29

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:63110 Martin AM, et al., Immunol Today. 2000;21(7):Centerfold
  • Latest
    J:226964 Yakkundi A, et al., FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):845-54

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory